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Astrovirus-induced epithelial-mesenchymal transition via activated TGF-β increases viral replication

Human astroviruses (HAstV), positive sense single-stranded RNA viruses, are one of the leading causes of diarrhea worldwide. Despite their high prevalence, the cellular mechanisms of astrovirus pathogenesis remain ill-defined. Previous studies showed HAstV increased epithelial barrier permeability b...

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Detalles Bibliográficos
Autores principales:	Hargest, Virginia, Bub, Theresa, Neale, Geoffrey, Schultz-Cherry, Stacey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067694/ https://www.ncbi.nlm.nih.gov/pubmed/35452499 http://dx.doi.org/10.1371/journal.ppat.1009716

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