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Abstract 158: Comparison of different screening tools for predicting osteoporosis in community dwelling post-menopausal women
Background: Dual-energy X-ray absorptiometry (DEXA) is gold standard in diagnosing osteoporosis. However, screening all postmenopausal women (PMW) for osteoporosis is not feasible in clinical practice. Questionaire based screening tools have still not been validated in Indian settings. Aims and Obje...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067712/ http://dx.doi.org/10.4103/2230-8210.342283 |
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author | Singhal, Vaibhav Kakaji, Manisha Awasthi, Ashish Gupta, Sushil Kumar |
author_facet | Singhal, Vaibhav Kakaji, Manisha Awasthi, Ashish Gupta, Sushil Kumar |
author_sort | Singhal, Vaibhav |
collection | PubMed |
description | Background: Dual-energy X-ray absorptiometry (DEXA) is gold standard in diagnosing osteoporosis. However, screening all postmenopausal women (PMW) for osteoporosis is not feasible in clinical practice. Questionaire based screening tools have still not been validated in Indian settings. Aims and Objectives: This cross-sectional study aimed to assess the performance of various osteoporosis-screening tools (OSTA, ORAI, SCORE, ABONE, BW, OSIRIS) in prediction of osteoporosis in PMW. Results: We enrolled 190 healthy middle-class community dwelling postmenopausal women (mean age 61.09 ± 6.5 years, range 50-86 years). The mean age of menopause was at 46.21 ± 4.9 years. Mean BMI was 27.92 ± 4.72 kg/m(2). Self reported fracture was present in 26.8% patients. BMD parameters showed osteoporosis in 63 (38.7%); osteopenia in 54 (33.1%) and normal in 46 patients (28.2%). Vitamin D deficiency (serum 25OHD <20 ng/ml) was present in majority (48.7%) of subjects. Clinically applicable screening tool for osteoporosis status were ABONE (AUC: 0.628) followed by the ORAI (AUC: 0.608, specificity 41%, Sensitivity- 97%). Conclusions: ABONE and ORAI clinical risk instruments demonstrate high sensitivity for predicting osteopororosis in PMW. These can help us identify individuals at high risk for osteoporosis and prioritize them for DEXA scanning. |
format | Online Article Text |
id | pubmed-9067712 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-90677122022-05-05 Abstract 158: Comparison of different screening tools for predicting osteoporosis in community dwelling post-menopausal women Singhal, Vaibhav Kakaji, Manisha Awasthi, Ashish Gupta, Sushil Kumar Indian J Endocrinol Metab Abstracts … Esicon 2021 Background: Dual-energy X-ray absorptiometry (DEXA) is gold standard in diagnosing osteoporosis. However, screening all postmenopausal women (PMW) for osteoporosis is not feasible in clinical practice. Questionaire based screening tools have still not been validated in Indian settings. Aims and Objectives: This cross-sectional study aimed to assess the performance of various osteoporosis-screening tools (OSTA, ORAI, SCORE, ABONE, BW, OSIRIS) in prediction of osteoporosis in PMW. Results: We enrolled 190 healthy middle-class community dwelling postmenopausal women (mean age 61.09 ± 6.5 years, range 50-86 years). The mean age of menopause was at 46.21 ± 4.9 years. Mean BMI was 27.92 ± 4.72 kg/m(2). Self reported fracture was present in 26.8% patients. BMD parameters showed osteoporosis in 63 (38.7%); osteopenia in 54 (33.1%) and normal in 46 patients (28.2%). Vitamin D deficiency (serum 25OHD <20 ng/ml) was present in majority (48.7%) of subjects. Clinically applicable screening tool for osteoporosis status were ABONE (AUC: 0.628) followed by the ORAI (AUC: 0.608, specificity 41%, Sensitivity- 97%). Conclusions: ABONE and ORAI clinical risk instruments demonstrate high sensitivity for predicting osteopororosis in PMW. These can help us identify individuals at high risk for osteoporosis and prioritize them for DEXA scanning. Wolters Kluwer - Medknow 2022-03 /pmc/articles/PMC9067712/ http://dx.doi.org/10.4103/2230-8210.342283 Text en Copyright: © 2022 Indian Journal of Endocrinology and Metabolism https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Abstracts … Esicon 2021 Singhal, Vaibhav Kakaji, Manisha Awasthi, Ashish Gupta, Sushil Kumar Abstract 158: Comparison of different screening tools for predicting osteoporosis in community dwelling post-menopausal women |
title | Abstract 158: Comparison of different screening tools for predicting osteoporosis in community dwelling post-menopausal women |
title_full | Abstract 158: Comparison of different screening tools for predicting osteoporosis in community dwelling post-menopausal women |
title_fullStr | Abstract 158: Comparison of different screening tools for predicting osteoporosis in community dwelling post-menopausal women |
title_full_unstemmed | Abstract 158: Comparison of different screening tools for predicting osteoporosis in community dwelling post-menopausal women |
title_short | Abstract 158: Comparison of different screening tools for predicting osteoporosis in community dwelling post-menopausal women |
title_sort | abstract 158: comparison of different screening tools for predicting osteoporosis in community dwelling post-menopausal women |
topic | Abstracts … Esicon 2021 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067712/ http://dx.doi.org/10.4103/2230-8210.342283 |
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