Abstract 119: Management of newly diagnosed type 2 diabetes mellitus with HBA1C > 10% in patients reluctant to take insulin

Background: Diabetes is pandemic in both developed and developing countries. In India there is great hesitancy to start insulin therapy either due to lack of knowledge, lack of storage facilities or financial constraints. Hence its important to find appropriate management protocols for the same. Aims and Objectives: To evaluate the efficacy of oral combination therapy with OHAs in newly diagnosed type 2 diabetes patients with HbA1c >10%. Result: We have observed a significant decrease in the HbA1c levels of both males and females at subsequent visits (p < 0.0001). The HbA1c values showed a statistically significant decrease from baseline to Follow up visit 1 for Males at 12.20 ± 1.99 to 6.67 ± 1.4 and for females from 12.36 ± 2.23 to 6.46 ± 1.76. Conclusion: Use of initial aggressive oral combination therapy with OHAs helped to achieve early optimal glycemic control. Initial HbA1c >10 % can be controlled with synergistic combinations of appropriate OHAs.initiation of insulin may not be required as suggested by all guidelines.