Abstract 130: Association between asymptomatic bacteriuria and serum Vitamin D in patients with type 2 diabetes

Background: Patients with type 2 diabetes (T2D are more frequently have asymptomatic bacteriuria (ASB). Vitamin D could play a protective role against ASB and urinary tract infections (UTI). Aims and Objective: To study the prevalence, clinical profile, and association between serum vitamin D level and ASB in T2D patients. Methods: This was a hospital based cross sectional study of adult T2D patients having age >18 years. The study recruited 150 T2D patients with no symptoms of UTI. Various clinical and biochemical parameters were monitored. Urine examination and culture and 25 OHD Vitamin D were monitored. Results: The mean age of the patients was 51.7±10.8 years, with mean glycated hemoglobin (HbA1c) of the subjects was 10.6±3.2%. The mean duration of diabetes was 8.2±4.1 years. The prevalence of ASB was 22 (14.7%) in T2D. ASB was significantly higher in females as compared to males. E. coli was the most common organism isolated from urine culture. The mean serum levels of 25 OHD among ASB patients was significantly lower than non-ASB (12.8±6.4 ng/ml vs 21.5±12.3 ng/ml; p < 0.001). No association was seen between ASB in males and vitamin D. Conclusion: ASB is associated with low vitamin D in T2D patients, in particular females.