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Tuberculosis in Greenland - Time from first contact to diagnosis and treatment

Tuberculosis (TB) is a persistent health issue in Greenland. While rapid diagnosis is crucial to reducing transmission of the disease, remote settlements have limited access to healthcare services. We aimed to assess and compare the time intervals from first contact to diagnosis and treatment for pa...

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Autores principales: Gleerup, Jens Lind, Vedsted, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067975/
https://www.ncbi.nlm.nih.gov/pubmed/35473468
http://dx.doi.org/10.1080/22423982.2022.2069220
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author Gleerup, Jens Lind
Vedsted, Peter
author_facet Gleerup, Jens Lind
Vedsted, Peter
author_sort Gleerup, Jens Lind
collection PubMed
description Tuberculosis (TB) is a persistent health issue in Greenland. While rapid diagnosis is crucial to reducing transmission of the disease, remote settlements have limited access to healthcare services. We aimed to assess and compare the time intervals from first contact to diagnosis and treatment for patients with active TB in the cities and settlements of Greenland. A total of 153 cases were included and divided according to place of residence and whether the diagnosis was based on symptomatic presentation or contact tracing. The median time from first contact to diagnosis was 19 days for the total population. The symptomatic settlement population waited longer (median = 88.5 days) than the symptomatic city population (median = 19 days) (p = 0.018). The system interval was longer for the symptomatic settlement population than for the symptomatic city population with a median of 49.5 days vs. 3 days for chest imaging (p < 0.001) and 66.5 days vs. 10 days for expectorate sample (p = 0.008). The diagnostic, system, and total intervals were significantly longer for symptomatic patients in settlements than in cities. This may explain a higher TB incidence in the settlements and calls for the development of better diagnostic pathways.
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spelling pubmed-90679752022-05-05 Tuberculosis in Greenland - Time from first contact to diagnosis and treatment Gleerup, Jens Lind Vedsted, Peter Int J Circumpolar Health Original Research Article Tuberculosis (TB) is a persistent health issue in Greenland. While rapid diagnosis is crucial to reducing transmission of the disease, remote settlements have limited access to healthcare services. We aimed to assess and compare the time intervals from first contact to diagnosis and treatment for patients with active TB in the cities and settlements of Greenland. A total of 153 cases were included and divided according to place of residence and whether the diagnosis was based on symptomatic presentation or contact tracing. The median time from first contact to diagnosis was 19 days for the total population. The symptomatic settlement population waited longer (median = 88.5 days) than the symptomatic city population (median = 19 days) (p = 0.018). The system interval was longer for the symptomatic settlement population than for the symptomatic city population with a median of 49.5 days vs. 3 days for chest imaging (p < 0.001) and 66.5 days vs. 10 days for expectorate sample (p = 0.008). The diagnostic, system, and total intervals were significantly longer for symptomatic patients in settlements than in cities. This may explain a higher TB incidence in the settlements and calls for the development of better diagnostic pathways. Taylor & Francis 2022-04-26 /pmc/articles/PMC9067975/ /pubmed/35473468 http://dx.doi.org/10.1080/22423982.2022.2069220 Text en © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research Article
Gleerup, Jens Lind
Vedsted, Peter
Tuberculosis in Greenland - Time from first contact to diagnosis and treatment
title Tuberculosis in Greenland - Time from first contact to diagnosis and treatment
title_full Tuberculosis in Greenland - Time from first contact to diagnosis and treatment
title_fullStr Tuberculosis in Greenland - Time from first contact to diagnosis and treatment
title_full_unstemmed Tuberculosis in Greenland - Time from first contact to diagnosis and treatment
title_short Tuberculosis in Greenland - Time from first contact to diagnosis and treatment
title_sort tuberculosis in greenland - time from first contact to diagnosis and treatment
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067975/
https://www.ncbi.nlm.nih.gov/pubmed/35473468
http://dx.doi.org/10.1080/22423982.2022.2069220
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