Cargando…

N-((1-(4-Fluorophenyl)-1H-1,2,3-triazol-4-yl)methyl)-2-methylene-3-oxo-olean-12-en-28-amide Induces Apoptosis in Human Breast Cancer Cells by Stimulating Oxidative Stress and Inhibiting the Notch-Akt Signaling Pathway

Breast cancer is of the leading causes of cancer-related deaths and the most frequently diagnosed cancer among females worldwide. Despite advancements in breast cancer therapy, the disease eventually progresses in most patients because of de novo or secondary resistance. Thus, discovering novel drug...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xiaorui, Wang, Shisheng, Deng, Ning, Guo, Xiangyu, Fu, Meiyi, Ma, Yiwen, Sun, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068303/ https://www.ncbi.nlm.nih.gov/pubmed/35528507 http://dx.doi.org/10.1155/2022/8123120

Ejemplares similares

Crystal structure of 1-(4-fluorophenyl)-4-(4-methoxyphenyl)-1H-1,2,3-triazole
por: Kumar, Balbir, et al.
Publicado: (2015)

5-(4-Fluorophenyl)-3-[5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazol-4-yl]-4,5-dihydro-1H-pyrazole-1-carbothioamide
por: Abdel-Wahab, Bakr F., et al.
Publicado: (2012)

3-Oxo-18α-olean-28,13β-olide
por: Santos, R. C., et al.
Publicado: (2010)

5-(4-Fluorophenyl)-3-[5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazol-4-yl]-N-phenyl-4,5-dihydro-1H-pyrazole-1-carbothioamide
por: Abdel-Wahab, Bakr F., et al.
Publicado: (2013)

1,4-Disubstituted 1,2,3-Triazoles as Amide Bond Surrogates for the Stabilisation of Linear Peptides with Biological Activity
por: Rečnik, Lisa-Maria, et al.
Publicado: (2020)

(E)-1-(1-Benzyl-5-methyl-1H-1,2,3-triazol-4-yl)-3-(4-fluorophenyl)prop-2-en-1-one
por: Fun, Hoong-Kun, et al.
Publicado: (2011)

1,2,3-Triazoles
por: Rachwal, S., et al.
Publicado: (2008)

Ethyl 2-[1-(3-methylbutyl)-4-phenyl-1H-1,2,3-triazol-5-yl]-2-oxoacetate
por: Ahmed, Muhammad Naeem, et al.
Publicado: (2013)

(2E)-3-(4-Fluorophenyl)-1-[5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazol-4-yl]prop-2-en-1-one
por: Abdel-Wahab, Bakr F., et al.
Publicado: (2013)

Methyl 1H-1,2,3-triazole-4-carboxylate
por: Prabakaran, K., et al.
Publicado: (2009)

Synthesis of (1,2,3-triazol-4-yl)methyl Phosphinates and (1,2,3-Triazol-4-yl)methyl Phosphates by Copper-Catalyzed Azide-Alkyne Cycloaddition
por: Tripolszky, Anna, et al.
Publicado: (2019)

1-Benzyl-4-(naphthalen-1-yl)-1H-1,2,3-triazole
por: Sarmiento-Sánchez, Juan I., et al.
Publicado: (2011)

3-Benzylsulfanyl-5-(4-phenyl-1H-1,2,3-triazol-1-ylmethyl)-4H-1,2,4-triazol-4-amine
por: Chu, Qing-Zhu, et al.
Publicado: (2008)

Synthesis methods of 1,2,3-/1,2,4-triazoles: A review
por: Dai, Jinlian, et al.
Publicado: (2022)

4-[5-(4-Fluorophenyl)-1-(4-phenyl-1,3-thiazol-2-yl)-4,5-dihydro-1H-pyrazol-3-yl]-5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazole
por: Abdel-Wahab, Bakr F., et al.
Publicado: (2013)

Methyl 1-methyl-1H-1,2,3-triazole-4-carboxylate
por: Khan, F. Nawaz, et al.
Publicado: (2010)

Methyl 1-benzyl-1H-1,2,3-triazole-4-carboxylate
por: Huang, Chiung-Cheng, et al.
Publicado: (2010)

Synthesis of 2-tetrafluoropyridyl-4,5-disubstituted 1,2,3-triazoles
por: Beyki, Khalil, et al.
Publicado: (2016)

Ethyl 2-{5-[(3-oxo-3,4-dihydro-2H-1,4-benzothiazin-4-yl)methyl]-1H-1,2,3-triazol-1-yl}acetate
por: Sebbar, Nada Kheira, et al.
Publicado: (2014)

5-Methyl-N′-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-1-phenyl-1H-1,2,3-triazole-4-carbohydrazide
por: Mohamed, Hanan A., et al.
Publicado: (2013)

Revisiting ring-degenerate rearrangements of 1-substituted-4-imino-1,2,3-triazoles
por: Fletcher, James T, et al.
Publicado: (2018)

A recent overview on the synthesis of 1,4,5-trisubstituted 1,2,3-triazoles
por: Shiri, Pezhman, et al.
Publicado: (2021)

5-(4-Hexyl-1H-1,2,3-triazol-1-yl)-2,1,3-benzoxadiazole
por: Key, Jessie A., et al.
Publicado: (2012)

5-(1-Benzyl-1H-1,2,3-triazol-4-yl)-2,1,3-benzoxadiazole
por: Key, Jessie A., et al.
Publicado: (2012)

4-{4-[(4-Oxoquinazolin-3-yl)methyl]-1H-1,2,3-triazol-1-yl}butyl acetate
por: Ouahrouch, Abdelaaziz, et al.
Publicado: (2011)

5-Methyl-1-phenyl-1H-1,2,3-triazole-4-carboxylic acid
por: Lin, Jin Rui, et al.
Publicado: (2008)

4-(4-Hydroxymethyl-1H-1,2,3-triazol-1-yl)benzoic acid
por: Ishak, Dayang Hazwani Abang, et al.
Publicado: (2011)

1,2,3-Triazole based bisphosphine, 5-(diphenylphosphanyl)-1-(2-(diphenylphosphanyl)-phenyl)-4-phenyl-1H-1,2,3-triazole: an ambidentate ligand with switchable coordination modes
por: Radhakrishna, Latchupatula, et al.
Publicado: (2018)

4-{1-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl}-5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazole
por: Abdel-Wahab, Bakr F., et al.
Publicado: (2012)

1-[4-Chloro-3-(trifluoromethyl)phenyl]-4-phenyl-1H-1,2,3-triazole
por: Altimari, Jarrad M., et al.
Publicado: (2012)

Propargylaminyl 3α-hydroxy-11-oxo-18β-olean-12-en-29-oate
por: Czollner, Laszlo, et al.
Publicado: (2011)

Synthesis and Antimicrobial Activity of 4-Substituted 1,2,3-Triazole-Coumarin Derivatives
por: López-Rojas, Priscila, et al.
Publicado: (2018)

Synthesis of Bis(1,2,3-Triazole) Functionalized Quinoline-2,4-Diones †
por: Milićević, David, et al.
Publicado: (2018)

Sensitive Energetics from the N‐Amination of 4‐Nitro‐1,2,3‐Triazole
por: Wozniak, Dominique R., et al.
Publicado: (2020)

Design and Synthesis of (2-oxo-1,2-Dihydroquinolin-4-yl)-1,2,3-triazole Derivatives via Click Reaction: Potential Apoptotic Antiproliferative Agents
por: El-Sheref, Essmat M., et al.
Publicado: (2021)

2-[1-(1-Naphthyl)-1H-1,2,3-triazol-4-yl]pyridine
por: Happ, Bobby, et al.
Publicado: (2009)

[1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl]methanol hemihydrate
por: Boechat, Nübia, et al.
Publicado: (2011)

1-(3-Bromopropyl)-4-(2-pyridyl)-1H-1,2,3-triazole
por: Crowley, James D., et al.
Publicado: (2009)

(1-Phenyl-1H-1,2,3-triazol-4-yl)methyl pyridine-3-carboxylate
por: Karimov, Zakirjon, et al.
Publicado: (2010)

1,2,3-Triazoles as Biomimetics in Peptide Science
por: Agouram, Naima, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_01b0ccbnuvj4jg10c0ilqv2m4b