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Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK

Parkinson's disease (PD) is a common neurodegenerative disease characterized by the degeneration of dopaminergic (DA) neurons in the substantia nigra (SN). Our previous study has shown that dexmedetomidine (Dex) can protect mitochondrial function and reduce apoptosis in MPP(+)-induced SH-SY5Y c...

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Detalles Bibliográficos
Autores principales:	Chen, Cheng, Chen, Yaohua, Liu, Tingting, Song, Dan, Ma, Di, Cheng, Oumei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068320/ https://www.ncbi.nlm.nih.gov/pubmed/35528513 http://dx.doi.org/10.1155/2022/7511393

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