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Opening of glutamate receptor channel to subconductance levels

Ionotropic glutamate receptors (iGluRs) are tetrameric ligand-gated ion channels that open their pores in response to binding of the agonist glutamate(1–3). An ionic current through a single iGluR channel shows up to four discrete conductance levels (O1–O4)(4–6). Higher conductance levels have been...

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Detalles Bibliográficos
Autores principales: Yelshanskaya, Maria V., Patel, Dhilon S., Kottke, Christopher M., Kurnikova, Maria G., Sobolevsky, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068512/
https://www.ncbi.nlm.nih.gov/pubmed/35444281
http://dx.doi.org/10.1038/s41586-022-04637-w