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High tumor mutational burden predicts worse prognosis for cervical cancer treated with radiotherapy
PURPOSE: Tumor mutational burden (TMB) is a surrogate biomarker of neo-antigens and high TMB status is associated with favorable response to immune-checkpoint inhibitors (ICIs). This study aimed to elucidate the association between TMB and the outcome of definitive radiotherapy in patients with cerv...
Autores principales: | Ota, Norichika, Yoshimoto, Yuya, Darwis, Narisa Dewi Maulany, Sato, Hiro, Ando, Ken, Oike, Takahiro, Ohno, Tatsuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068645/ https://www.ncbi.nlm.nih.gov/pubmed/34860358 http://dx.doi.org/10.1007/s11604-021-01230-5 |
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