Cargando…

High tumor mutational burden predicts worse prognosis for cervical cancer treated with radiotherapy

PURPOSE: Tumor mutational burden (TMB) is a surrogate biomarker of neo-antigens and high TMB status is associated with favorable response to immune-checkpoint inhibitors (ICIs). This study aimed to elucidate the association between TMB and the outcome of definitive radiotherapy in patients with cerv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ota, Norichika, Yoshimoto, Yuya, Darwis, Narisa Dewi Maulany, Sato, Hiro, Ando, Ken, Oike, Takahiro, Ohno, Tatsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Nature Singapore 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068645/ https://www.ncbi.nlm.nih.gov/pubmed/34860358 http://dx.doi.org/10.1007/s11604-021-01230-5

Ejemplares similares

Characteristics of PSA Bounce after Radiotherapy for Prostate Cancer: A Meta-Analysis
por: Darwis, Narisa Dewi Maulany, et al.
Publicado: (2020)

Comparison of Clonogenic Survival Data Obtained by Pre- and Post-Irradiation Methods
por: Oike, Takahiro, et al.
Publicado: (2020)

Reporting of methodologies used for clonogenic assays to determine radiosensitivity
por: Oike, Takahiro, et al.
Publicado: (2020)

Association between Tumor Mutational Burden, Stromal CD8(+) Tumor-Infiltrating Lymphocytes, and Clinical Factors in Cervical Cancers Treated with Radiotherapy
por: Ruan, Hanguang, et al.
Publicado: (2023)

Radiosensitization by the Selective Pan-FGFR Inhibitor LY2874455
por: Darwis, Narisa Dewi Maulany, et al.
Publicado: (2022)

Kinetics of Prostate-Specific Antigen after Carbon Ion Radiotherapy for Prostate Cancer
por: Darwis, Narisa Dewi Maulany, et al.
Publicado: (2020)

Radiotherapy With Hydrogen Peroxide-Soaked Gauze for Preauricular Sebaceous Carcinoma
por: Adachi, Akiko, et al.
Publicado: (2022)

Granulocyte‐colony stimulating factor‐producing uterine cervical cancer treated with chemoradiotherapy: A case report with mutation analysis and literature review
por: Shiba, Shintaro, et al.
Publicado: (2020)

Induction of Micronuclei in Cervical Cancer Treated with Radiotherapy
por: Kobayashi, Daijiro, et al.
Publicado: (2020)

Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy
por: Okada, Kohei, et al.
Publicado: (2021)

The Non-Cancer Specific Elevation of the Serum Squamous Cell Carcinoma Antigen during the Post-Radiotherapy Follow-Up of Cervical Cancer Patients
por: Oike, Tae, et al.
Publicado: (2021)

Mutation Analysis of Radioresistant Early-Stage Cervical Cancer
por: Oike, Tae, et al.
Publicado: (2021)

FGFR Signaling as a Candidate Therapeutic Target for Cancers Resistant to Carbon Ion Radiotherapy
por: Darwis, Narisa Dewi Maulany, et al.
Publicado: (2019)

Comparison of hematological toxicities between innovator and generic cisplatin formulations in cervical cancer patients treated with concurrent chemoradiotherapy
por: Oike, Takahiro, et al.
Publicado: (2013)

Mutational analysis of uterine cervical cancer that survived multiple rounds of radiotherapy
por: Nuryadi, Endang, et al.
Publicado: (2018)

Rectovaginal fistula in a cervical cancer patient treated with sequential radiotherapy and bevacizumab: A dose‐volume analysis
por: Tomizawa, Kento, et al.
Publicado: (2021)

Palliative radiation therapy for bleeding from gastric cancer: A case series of seven patients
por: Ota, Norichika, et al.
Publicado: (2023)

Pilot study of plasma creatine riboside as a potential biomarker for cervical cancer
por: Oike, Takahiro, et al.
Publicado: (2023)

Radiotherapy-Induced Anti-Tumor Immunity Contributes to the Therapeutic Efficacy of Irradiation and Can Be Augmented by CTLA-4 Blockade in a Mouse Model
por: Yoshimoto, Yuya, et al.
Publicado: (2014)

Phase I Study of Carbon Ion Radiotherapy and Image-Guided Brachytherapy for Locally Advanced Cervical Cancer
por: Ohno, Tatsuya, et al.
Publicado: (2018)

Colorectal Cancer Screening Outcomes of 2412 Prostate Cancer Patients Considered for Carbon Ion Radiotherapy
por: Kobayashi, Nao, et al.
Publicado: (2021)

Patient-Derived Training Simulator for Image-Guided Adaptive Brachytherapy of Locally Advanced Cervical Cancers: Development and Initial Use
por: Tomizawa, Kento, et al.
Publicado: (2022)

Inguinal hernia in a patient with prostate cancer to be treated with photon radiotherapy
por: Oike, Takahiro, et al.
Publicado: (2020)

The role of radiotherapy in the age of immunotherapy
por: Sato, Hiro, et al.
Publicado: (2021)

Stereotactic body radiotherapy for adenoid cystic carcinoma metastatic to the lung: a case report
por: Kobayashi, Daijiro, et al.
Publicado: (2021)

Carbon-ion beams induce production of an immune mediator protein, high mobility group box 1, at levels comparable with X-ray irradiation
por: Yoshimoto, Yuya, et al.
Publicado: (2015)

A retrospective study of small-pelvis radiotherapy plus image-guided brachytherapy in stage I–II non-bulky cervical squamous cell carcinoma
por: Yoshimoto, Yuya, et al.
Publicado: (2022)

Translational Research to Improve the Efficacy of Carbon Ion Radiotherapy: Experience of Gunma University
por: Oike, Takahiro, et al.
Publicado: (2016)

Can combined intracavitary/interstitial approach be an alternative to interstitial brachytherapy with the Martinez Universal Perineal Interstitial Template (MUPIT) in computed tomography-guided adaptive brachytherapy for bulky and/or irregularly shaped gynecological tumors?
por: Oike, Takahiro, et al.
Publicado: (2014)

Radio-sensitization effect of an mTOR inhibitor, temsirolimus, on lung adenocarcinoma A549 cells under normoxic and hypoxic conditions
por: Ushijima, Hiroki, et al.
Publicado: (2015)

Unresectable cutaneous metastatic tumor in the arm that underwent complete remission after radiotherapy
por: Oike, Takahiro, et al.
Publicado: (2020)

High linear energy transfer carbon-ion irradiation increases the release of the immune mediator high mobility group box 1 from human cancer cells
por: Onishi, Masahiro, et al.
Publicado: (2018)

Leptomeningeal metastasis of uterine cervical cancer 17 years after primary tumor treatment
por: Oike, Takahiro, et al.
Publicado: (2015)

Radiotherapy With Hydrogen Peroxide-Soaked Gauze for Unresectable Breast Cancer
por: Oike, Takahiro, et al.
Publicado: (2021)

HLA Class I Expression and Its Alteration by Preoperative Hyperthermo-Chemoradiotherapy in Patients with Rectal Cancer
por: Sato, Hiro, et al.
Publicado: (2014)

(64)Cu-ATSM Predicts Efficacy of Carbon Ion Radiotherapy Associated with Cellular Antioxidant Capacity
por: Nachankar, Ankita, et al.
Publicado: (2021)

Oral Gastrografin Facilitates Delineation of Intestinal Tracts in CT-Based Brachytherapy for Uterine Cervical Cancer
por: Irie, Daisuke, et al.
Publicado: (2020)

Skin Dose Reduction by Layer-Stacking Irradiation in Carbon Ion Radiotherapy for Parotid Tumors
por: Kubo, Nobuteru, et al.
Publicado: (2020)

Efficacy of immune checkpoint inhibitor treatment for head and neck mucosal melanoma recurrence in patients treated with carbon‐ion radiotherapy
por: Musha, Atsushi, et al.
Publicado: (2023)

Relative Biological Effectiveness of Carbon Ions for Head-and-Neck Squamous Cell Carcinomas According to Human Papillomavirus Status
por: Osu, Naoto, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_94edjrd398l0e0n0q9tst2euon