Pre-transplant infusion of donor leukocytes treated with extracorporeal photochemotherapy induces immune hypo-responsiveness and long-term allograft survival in murine models

Recipients of solid organ transplantation (SOT) rely on life-long immunosuppression (IS), which is associated with significant side effects. Extracorporeal photochemotherapy (ECP) is a safe, existing cellular therapy used to treat transplant rejection by modulating the recipient’s own blood cells. W...

Descripción completa

Detalles Bibliográficos
Autores principales: Schneiderman, Jennifer, Qiu, Longhui, Yeap, Xin Yi, Kang, Xin, Zheng, Feibo, Ye, Junsheng, Xie, Yan, Wang, Jiao-Jing, Sambandam, Yuvaraj, Mathew, James, Li, Lin, Leventhal, Joseph, Edelson, Richard L., Zhang, Zheng Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068706/
https://www.ncbi.nlm.nih.gov/pubmed/35508582
http://dx.doi.org/10.1038/s41598-022-11290-w

Ejemplares similares

Ejemplares similares