YTHDF1 alleviates sepsis by upregulating WWP1 to induce NLRP3 ubiquitination and inhibit caspase-1-dependent pyroptosis

Pyroptosis is inflammation-associated caspase-1-dependent programmed cell death, which confers a crucial role in sepsis. The present study intends to investigate the regulatory network and function of the microarray-predicted YTHDF1 in caspase-1-dependent pyroptosis of sepsis. Peripheral blood of pa...

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Detalles Bibliográficos
Autores principales: Zhang, Shuyao, Guan, Xinmin, Liu, Wei, Zhu, Zhe, Jin, Hong, Zhu, Youfeng, Chen, Yun, Zhang, Min, Xu, Chengcheng, Tang, Xu, Wang, Jing, Cheng, Wang, Lin, Weihua, Ma, Xiaoke, Chen, Jianliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068740/
https://www.ncbi.nlm.nih.gov/pubmed/35508474
http://dx.doi.org/10.1038/s41420-022-00872-2

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