Transdermal permeation of curcumin promoted by choline geranate ionic liquid: Potential for the treatment of skin diseases

The transdermal permeation of curcumin aided by choline and geranic acid ionic liquid (CAGE-IL) was addressed as a potential treatment for skin diseases. An in-depth analysis of the effect of CAGE-IL concentration in the enhancement of transdermal permeation of curcumin was performed, and the result...

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Detalles Bibliográficos
Autores principales: Boscariol, Rodrigo, Oliveira Junior, José M., Baldo, Denicezar A., Balcão, Victor M., Vila, Marta M.D.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068761/
https://www.ncbi.nlm.nih.gov/pubmed/35527836
http://dx.doi.org/10.1016/j.jsps.2022.01.023
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author Boscariol, Rodrigo
Oliveira Junior, José M.
Baldo, Denicezar A.
Balcão, Victor M.
Vila, Marta M.D.C.
author_facet Boscariol, Rodrigo
Oliveira Junior, José M.
Baldo, Denicezar A.
Balcão, Victor M.
Vila, Marta M.D.C.
author_sort Boscariol, Rodrigo
collection PubMed
description The transdermal permeation of curcumin aided by choline and geranic acid ionic liquid (CAGE-IL) was addressed as a potential treatment for skin diseases. An in-depth analysis of the effect of CAGE-IL concentration in the enhancement of transdermal permeation of curcumin was performed, and the results were modelled via nonlinear regression analysis. The results obtained showed that a low percentage of CAGE-IL (viz. 2.0%, w/w) was effective in disrupting the skin structure in a transient fashion, facilitating the passage of curcumin dissolved in it.
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spelling pubmed-90687612022-05-05 Transdermal permeation of curcumin promoted by choline geranate ionic liquid: Potential for the treatment of skin diseases Boscariol, Rodrigo Oliveira Junior, José M. Baldo, Denicezar A. Balcão, Victor M. Vila, Marta M.D.C. Saudi Pharm J Original Article The transdermal permeation of curcumin aided by choline and geranic acid ionic liquid (CAGE-IL) was addressed as a potential treatment for skin diseases. An in-depth analysis of the effect of CAGE-IL concentration in the enhancement of transdermal permeation of curcumin was performed, and the results were modelled via nonlinear regression analysis. The results obtained showed that a low percentage of CAGE-IL (viz. 2.0%, w/w) was effective in disrupting the skin structure in a transient fashion, facilitating the passage of curcumin dissolved in it. Elsevier 2022-04 2022-02-04 /pmc/articles/PMC9068761/ /pubmed/35527836 http://dx.doi.org/10.1016/j.jsps.2022.01.023 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Boscariol, Rodrigo
Oliveira Junior, José M.
Baldo, Denicezar A.
Balcão, Victor M.
Vila, Marta M.D.C.
Transdermal permeation of curcumin promoted by choline geranate ionic liquid: Potential for the treatment of skin diseases
title Transdermal permeation of curcumin promoted by choline geranate ionic liquid: Potential for the treatment of skin diseases
title_full Transdermal permeation of curcumin promoted by choline geranate ionic liquid: Potential for the treatment of skin diseases
title_fullStr Transdermal permeation of curcumin promoted by choline geranate ionic liquid: Potential for the treatment of skin diseases
title_full_unstemmed Transdermal permeation of curcumin promoted by choline geranate ionic liquid: Potential for the treatment of skin diseases
title_short Transdermal permeation of curcumin promoted by choline geranate ionic liquid: Potential for the treatment of skin diseases
title_sort transdermal permeation of curcumin promoted by choline geranate ionic liquid: potential for the treatment of skin diseases
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068761/
https://www.ncbi.nlm.nih.gov/pubmed/35527836
http://dx.doi.org/10.1016/j.jsps.2022.01.023
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