Concurrent outcomes from multiple approaches of epistasis analysis for human body mass index associated loci provide insights into obesity biology

Genome wide association studies (GWAS) have focused on elucidating the genetic architecture of complex traits by assessing single variant effects in additive genetic models, albeit explaining a fraction of the trait heritability. Epistasis has recently emerged as one of the intrinsic mechanisms that...

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Detalles Bibliográficos
Autores principales: D’Silva, Sheldon, Chakraborty, Shreya, Kahali, Bratati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068779/
https://www.ncbi.nlm.nih.gov/pubmed/35508500
http://dx.doi.org/10.1038/s41598-022-11270-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068779/
https://www.ncbi.nlm.nih.gov/pubmed/35508500
http://dx.doi.org/10.1038/s41598-022-11270-0

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