Cargando…
Concurrent outcomes from multiple approaches of epistasis analysis for human body mass index associated loci provide insights into obesity biology
Genome wide association studies (GWAS) have focused on elucidating the genetic architecture of complex traits by assessing single variant effects in additive genetic models, albeit explaining a fraction of the trait heritability. Epistasis has recently emerged as one of the intrinsic mechanisms that...
Autores principales: | D’Silva, Sheldon, Chakraborty, Shreya, Kahali, Bratati |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068779/ https://www.ncbi.nlm.nih.gov/pubmed/35508500 http://dx.doi.org/10.1038/s41598-022-11270-0 |
Ejemplares similares
-
Exome-wide analysis reveals role of LRP1 and additional novel loci in cognition
por: Chakraborty, Shreya, et al.
Publicado: (2023) -
Genome-wide analysis of epistasis in body mass index using multiple human populations
por: Wei, Wen-Hua, et al.
Publicado: (2012) -
Protein complex forming ability is favored over the features of interacting partners in determining the evolutionary rates of proteins in the yeast protein-protein interaction networks
por: Chakraborty, Sandip, et al.
Publicado: (2010) -
Machine learning‐based cognitive impairment classification with optimal combination of neuropsychological tests
por: Gupta, Abhay, et al.
Publicado: (2020) -
Models and partition of variance for quantitative trait loci with epistasis and linkage disequilibrium
por: Wang, Tao, et al.
Publicado: (2006)