Nobiletin ameliorates high fat-induced disruptions in rhythmic glucagon-like peptide-1 secretion

The incretin hormone glucagon-like peptide-1 (GLP-1) is secreted by the intestinal L cell in response to nutrient intake. However, GLP-1 secretion also follows a circadian rhythm which is disrupted by the saturated fatty acid palmitate in vitro and high-fat diet (HFD) feeding in vivo. The flavonoid...

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Detalles Bibliográficos
Autores principales: Martchenko, Alexandre, Biancolin, Andrew D., Martchenko, Sarah E., Brubaker, Patricia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068808/
https://www.ncbi.nlm.nih.gov/pubmed/35508494
http://dx.doi.org/10.1038/s41598-022-11223-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068808/
https://www.ncbi.nlm.nih.gov/pubmed/35508494
http://dx.doi.org/10.1038/s41598-022-11223-7

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