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Nobiletin ameliorates high fat-induced disruptions in rhythmic glucagon-like peptide-1 secretion
The incretin hormone glucagon-like peptide-1 (GLP-1) is secreted by the intestinal L cell in response to nutrient intake. However, GLP-1 secretion also follows a circadian rhythm which is disrupted by the saturated fatty acid palmitate in vitro and high-fat diet (HFD) feeding in vivo. The flavonoid...
Autores principales: | Martchenko, Alexandre, Biancolin, Andrew D., Martchenko, Sarah E., Brubaker, Patricia L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068808/ https://www.ncbi.nlm.nih.gov/pubmed/35508494 http://dx.doi.org/10.1038/s41598-022-11223-7 |
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