Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandrathibetica

Phytochemical reinvestigation on the whole plants of Ypsilandra thibetica obtained four new spirostanol glycosides, named ypsilandrosides U-X (1–4), and one new cholestanol glycoside, named ypsilandroside Y (5). Their structures have been established by extensive spectroscopic data and chemical meth...

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Autores principales: Gao, Wen-Tao, Yu, Ling-Ling, Xie, Jing, Xiao, Long-Gao, Zhang, Shi-Juan, Ma, Wen-Yi, Yan, Huan, Liu, Hai-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068850/
https://www.ncbi.nlm.nih.gov/pubmed/35508749
http://dx.doi.org/10.1007/s13659-022-00337-0
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author Gao, Wen-Tao
Yu, Ling-Ling
Xie, Jing
Xiao, Long-Gao
Zhang, Shi-Juan
Ma, Wen-Yi
Yan, Huan
Liu, Hai-Yang
author_facet Gao, Wen-Tao
Yu, Ling-Ling
Xie, Jing
Xiao, Long-Gao
Zhang, Shi-Juan
Ma, Wen-Yi
Yan, Huan
Liu, Hai-Yang
author_sort Gao, Wen-Tao
collection PubMed
description Phytochemical reinvestigation on the whole plants of Ypsilandra thibetica obtained four new spirostanol glycosides, named ypsilandrosides U-X (1–4), and one new cholestanol glycoside, named ypsilandroside Y (5). Their structures have been established by extensive spectroscopic data and chemical methods. Among them, compound 4 is a rare spirostanol glycoside which possesses a novel 5(6 → 7) abeo-steroidal aglycone, while compound 1 is a first spirostanol bisdesmoside attached to C-3 and C-12, respectively, isolated from the genus Ypsilandra. The induced platelet aggregation activity of the isolates was tested. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13659-022-00337-0.
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spelling pubmed-90688502022-05-07 Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandrathibetica Gao, Wen-Tao Yu, Ling-Ling Xie, Jing Xiao, Long-Gao Zhang, Shi-Juan Ma, Wen-Yi Yan, Huan Liu, Hai-Yang Nat Prod Bioprospect Original Article Phytochemical reinvestigation on the whole plants of Ypsilandra thibetica obtained four new spirostanol glycosides, named ypsilandrosides U-X (1–4), and one new cholestanol glycoside, named ypsilandroside Y (5). Their structures have been established by extensive spectroscopic data and chemical methods. Among them, compound 4 is a rare spirostanol glycoside which possesses a novel 5(6 → 7) abeo-steroidal aglycone, while compound 1 is a first spirostanol bisdesmoside attached to C-3 and C-12, respectively, isolated from the genus Ypsilandra. The induced platelet aggregation activity of the isolates was tested. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13659-022-00337-0. Springer Singapore 2022-05-05 /pmc/articles/PMC9068850/ /pubmed/35508749 http://dx.doi.org/10.1007/s13659-022-00337-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Gao, Wen-Tao
Yu, Ling-Ling
Xie, Jing
Xiao, Long-Gao
Zhang, Shi-Juan
Ma, Wen-Yi
Yan, Huan
Liu, Hai-Yang
Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandrathibetica
title Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandrathibetica
title_full Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandrathibetica
title_fullStr Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandrathibetica
title_full_unstemmed Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandrathibetica
title_short Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandrathibetica
title_sort ypsilandrosides u-y, five new steroidal saponins from ypsilandrathibetica
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068850/
https://www.ncbi.nlm.nih.gov/pubmed/35508749
http://dx.doi.org/10.1007/s13659-022-00337-0
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