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Study on the Characteristics of Small-Molecule Kinase Inhibitors-Related Drug-Induced Liver Injury

Background and Aim: More than half of the small-molecule kinase inhibitors (KIs) induced liver injury clinically. Meanwhile, studies have shown a close relationship between mitochondrial damage and drug-induced liver injury (DILI). We aimed to study KIs and the binding between drugs and mitochondria...

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Detalles Bibliográficos
Autores principales:	Dong, Huiqun, You, Jia, Zhao, Yu, Zheng, Danhua, Zhong, Yi, Li, Gaozheng, Weng, Zuquan, Luo, Heng, Jiang, Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068902/ https://www.ncbi.nlm.nih.gov/pubmed/35529445 http://dx.doi.org/10.3389/fphar.2022.838397

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