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Microgravity crystallization of perdeuterated tryptophan synthase for neutron diffraction

Biologically active vitamin B(6)-derivative pyridoxal 5′-phosphate (PLP) is an essential cofactor in amino acid metabolic pathways. PLP-dependent enzymes catalyze a multitude of chemical reactions but, how reaction diversity of PLP-dependent enzymes is achieved is still not well understood. Such com...

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Detalles Bibliográficos
Autores principales:	Drago, Victoria N., Devos, Juliette M., Blakeley, Matthew P., Forsyth, V. Trevor, Kovalevsky, Andrey Y., Schall, Constance A., Mueser, Timothy C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068912/ https://www.ncbi.nlm.nih.gov/pubmed/35508463 http://dx.doi.org/10.1038/s41526-022-00199-3

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