Functional Interaction Between the Oncogenic Kinase NEK2 and Sam68 Promotes a Splicing Program Involved in Migration and Invasion in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) represents the most aggressive breast cancer subtype. Poor prognosis in TNBC is partly due to lack of efficacious targeted therapy and high propensity to metastasize. Dysregulation of alternative splicing has recently emerged as a trait of TNBC, suggesting that u...

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Detalles Bibliográficos
Autores principales: Naro, Chiara, Barbagallo, Federica, Caggiano, Cinzia, De Musso, Monica, Panzeri, Valentina, Di Agostino, Silvia, Paronetto, Maria Paola, Sette, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068942/
https://www.ncbi.nlm.nih.gov/pubmed/35530315
http://dx.doi.org/10.3389/fonc.2022.880654

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