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Nanopore Sequencing for Detection and Characterization of Phosphorothioate Modifications in Native DNA Sequences

Bacterial DNA is subject to various modifications involved in gene regulation and defense against bacteriophage attacks. Phosphorothioate (PT) modifications are protective modifications in which the non-bridging oxygen in the DNA phosphate backbone is replaced with a sulfur atom. Here, we expand thi...

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Detalles Bibliográficos
Autores principales:	Wadley, Taylor, Moon, Sun Hee, DeMott, Michael S., Wanchai, Visanu, Huang, En, Dedon, Peter C., Boysen, Gunnar, Nookaew, Intawat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069010/ https://www.ncbi.nlm.nih.gov/pubmed/35531280 http://dx.doi.org/10.3389/fmicb.2022.871937

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