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Distinct Functional Metagenomic Markers Predict the Responsiveness to Anti-PD-1 Therapy in Chinese Non-Small Cell Lung Cancer Patients
BACKGROUND: Programmed death 1 (PD-1) and the ligand of PD-1 (PD-L1) are central targets for immune-checkpoint therapy (ICT) blocking immune evasion-related pathways elicited by tumor cells. A number of PD-1 inhibitors have been developed, but the efficacy of these inhibitors varies considerably and...
Autores principales: | Fang, Chao, Fang, Wenfeng, Xu, Liqin, Gao, Fangfang, Hou, Yong, Zou, Hua, Ma, Yuxiang, Moll, Janne Marie, Yang, Yunpeng, Wang, Dan, Huang, Yan, Ren, Huahui, Zhao, Hongyun, Qin, Shishang, Zhong, Huanzi, Li, Junhua, Liu, Sheng, Yang, Huanming, Wang, Jian, Brix, Susanne, Kristiansen, Karsten, Zhang, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069064/ https://www.ncbi.nlm.nih.gov/pubmed/35530307 http://dx.doi.org/10.3389/fonc.2022.837525 |
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