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Idiopathic Epiretinal Membranes: Visual Outcomes and Prognostic Factors

OBJECTIVES: To evaluate the associations between anatomical changes and visual outcomes in patients with idiopathic epiretinal membrane (ERM). MATERIALS AND METHODS: We performed a prospective study of 130 consecutive idiopathic ERM patients and report their visual outcomes and the factors associate...

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Autores principales: Kunavisarut, Paradee, Supawongwattana, Montana, Patikulsila, Direk, Choovuthayakorn, Janejit, Watanachai, Nawat, Chaikitmongkol, Voraporn, Pathanapitoon, Kessara, Rothova, Aniki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069092/
https://www.ncbi.nlm.nih.gov/pubmed/35481732
http://dx.doi.org/10.4274/tjo.galenos.2021.09258
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author Kunavisarut, Paradee
Supawongwattana, Montana
Patikulsila, Direk
Choovuthayakorn, Janejit
Watanachai, Nawat
Chaikitmongkol, Voraporn
Pathanapitoon, Kessara
Rothova, Aniki
author_facet Kunavisarut, Paradee
Supawongwattana, Montana
Patikulsila, Direk
Choovuthayakorn, Janejit
Watanachai, Nawat
Chaikitmongkol, Voraporn
Pathanapitoon, Kessara
Rothova, Aniki
author_sort Kunavisarut, Paradee
collection PubMed
description OBJECTIVES: To evaluate the associations between anatomical changes and visual outcomes in patients with idiopathic epiretinal membrane (ERM). MATERIALS AND METHODS: We performed a prospective study of 130 consecutive idiopathic ERM patients and report their visual outcomes and the factors associated with visual outcome and anatomical changes. RESULTS: Of 130 eyes of 130 patients, 87 eyes underwent surgery, while the remaining 43 eyes were observed. At 6-month follow-up, the best-corrected visual acuity (BCVA) increased in the whole population. Mean Early Treatment Diabetic Retinopathy Study letter score changed from 51 to 65 in the surgical group and from 67 to 68 in the non-surgical group. The surgical group had improvement in BCVA at all ERM stages and grades of disorganization of the retinal inner layers (DRIL) (p<0.01). In multivariable analysis of the surgical group, factors associated with BCVA of ETDRS 60 letters or more were no or mild DRIL and the absence of ellipsoid zone disruption at baseline (p=0.002 and p=0.034, respectively) and this statistically significant positive correlation was still maintained at 12-month follow-up. CONCLUSION: Baseline DRIL grade and presence of ellipsoid zone disruption were the most informative prognostic factors in patients with idiopathic ERMs. Patients with severe DRIL and/or advanced ERMs had improved vision after ERM removal.
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spelling pubmed-90690922022-05-13 Idiopathic Epiretinal Membranes: Visual Outcomes and Prognostic Factors Kunavisarut, Paradee Supawongwattana, Montana Patikulsila, Direk Choovuthayakorn, Janejit Watanachai, Nawat Chaikitmongkol, Voraporn Pathanapitoon, Kessara Rothova, Aniki Turk J Ophthalmol Original Article OBJECTIVES: To evaluate the associations between anatomical changes and visual outcomes in patients with idiopathic epiretinal membrane (ERM). MATERIALS AND METHODS: We performed a prospective study of 130 consecutive idiopathic ERM patients and report their visual outcomes and the factors associated with visual outcome and anatomical changes. RESULTS: Of 130 eyes of 130 patients, 87 eyes underwent surgery, while the remaining 43 eyes were observed. At 6-month follow-up, the best-corrected visual acuity (BCVA) increased in the whole population. Mean Early Treatment Diabetic Retinopathy Study letter score changed from 51 to 65 in the surgical group and from 67 to 68 in the non-surgical group. The surgical group had improvement in BCVA at all ERM stages and grades of disorganization of the retinal inner layers (DRIL) (p<0.01). In multivariable analysis of the surgical group, factors associated with BCVA of ETDRS 60 letters or more were no or mild DRIL and the absence of ellipsoid zone disruption at baseline (p=0.002 and p=0.034, respectively) and this statistically significant positive correlation was still maintained at 12-month follow-up. CONCLUSION: Baseline DRIL grade and presence of ellipsoid zone disruption were the most informative prognostic factors in patients with idiopathic ERMs. Patients with severe DRIL and/or advanced ERMs had improved vision after ERM removal. Galenos Publishing 2022-04 2022-04-28 /pmc/articles/PMC9069092/ /pubmed/35481732 http://dx.doi.org/10.4274/tjo.galenos.2021.09258 Text en © Copyright 2022 by Turkish Ophthalmological Association | Turkish Journal of Ophthalmology, published by Galenos Publishing House. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kunavisarut, Paradee
Supawongwattana, Montana
Patikulsila, Direk
Choovuthayakorn, Janejit
Watanachai, Nawat
Chaikitmongkol, Voraporn
Pathanapitoon, Kessara
Rothova, Aniki
Idiopathic Epiretinal Membranes: Visual Outcomes and Prognostic Factors
title Idiopathic Epiretinal Membranes: Visual Outcomes and Prognostic Factors
title_full Idiopathic Epiretinal Membranes: Visual Outcomes and Prognostic Factors
title_fullStr Idiopathic Epiretinal Membranes: Visual Outcomes and Prognostic Factors
title_full_unstemmed Idiopathic Epiretinal Membranes: Visual Outcomes and Prognostic Factors
title_short Idiopathic Epiretinal Membranes: Visual Outcomes and Prognostic Factors
title_sort idiopathic epiretinal membranes: visual outcomes and prognostic factors
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069092/
https://www.ncbi.nlm.nih.gov/pubmed/35481732
http://dx.doi.org/10.4274/tjo.galenos.2021.09258
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