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Deletion of Non-histidine Domains of Histidine Kinase CHK1 Diminishes the Infectivity of Candida albicans in an Oral Mucosal Model
OBJECTIVES: The histidine kinase (HK) CHK1 and other protein kinases in Candida albicans are key players in the development of hyphae. This study is designed to determine the functional roles of the S_Tkc domain (protein kinase) and the GAF domain of C. albicans CHK1 in hyphal formation and mucosal...
Autores principales: | Feng, Yahui, Bian, Shaodong, Pang, Zhiping, Wen, Yiyang, Calderone, Richard, Li, Dongmei, Shi, Dongmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069115/ https://www.ncbi.nlm.nih.gov/pubmed/35531278 http://dx.doi.org/10.3389/fmicb.2022.855651 |
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