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Deletion of Non-histidine Domains of Histidine Kinase CHK1 Diminishes the Infectivity of Candida albicans in an Oral Mucosal Model

OBJECTIVES: The histidine kinase (HK) CHK1 and other protein kinases in Candida albicans are key players in the development of hyphae. This study is designed to determine the functional roles of the S_Tkc domain (protein kinase) and the GAF domain of C. albicans CHK1 in hyphal formation and mucosal...

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Detalles Bibliográficos
Autores principales: Feng, Yahui, Bian, Shaodong, Pang, Zhiping, Wen, Yiyang, Calderone, Richard, Li, Dongmei, Shi, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069115/
https://www.ncbi.nlm.nih.gov/pubmed/35531278
http://dx.doi.org/10.3389/fmicb.2022.855651

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