The individual and global impact of copy-number variants on complex human traits

The impact of copy-number variations (CNVs) on complex human traits remains understudied. We called CNVs in 331,522 UK Biobank participants and performed genome-wide association studies (GWASs) between the copy number of CNV-proxy probes and 57 continuous traits, revealing 131 signals spanning 47 ph...

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Detalles Bibliográficos
Autores principales: Auwerx, Chiara, Lepamets, Maarja, Sadler, Marie C., Patxot, Marion, Stojanov, Miloš, Baud, David, Mägi, Reedik, Porcu, Eleonora, Reymond, Alexandre, Kutalik, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069145/
https://www.ncbi.nlm.nih.gov/pubmed/35240056
http://dx.doi.org/10.1016/j.ajhg.2022.02.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069145/
https://www.ncbi.nlm.nih.gov/pubmed/35240056
http://dx.doi.org/10.1016/j.ajhg.2022.02.010

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