Cargando…

Pharmacological Perturbation of Mechanical Contractility Enables Robust Transdifferentiation of Human Fibroblasts into Neurons

Direct cell reprogramming, also called transdifferentiation, is valuable for cell fate studies and regenerative medicine. Current approaches to transdifferentiation are usually achieved by directly targeting the nuclear functions, such as manipulating the lineage‐specific transcriptional factors, mi...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Zheng‐Quan, Li, Yu‐Huan, Feng, Gui‐Hai, Yuan, Xue‐Wei, Lu, Zong‐Bao, Dai, Min, Hu, Yan‐Ping, Zhang, Ying, Zhou, Qi, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069193/
https://www.ncbi.nlm.nih.gov/pubmed/35240008
http://dx.doi.org/10.1002/advs.202104682