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Effects of linker and liposome anchoring on lactose-functionalized glycomacromolecules as multivalent ligands for binding galectin-3

In this work, we present a bottom-up approach for the synthesis of lactose-functionalized glycomacromolecules and glycofunctionalized liposomes and apply these compounds to investigate their effects of multivalent presentation on binding to galectin-3. Step-wise assembly of tailor-made building bloc...

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Detalles Bibliográficos
Autores principales:	Freichel, Tanja, Laaf, Dominic, Hoffmann, Miriam, Konietzny, Patrick B., Heine, Viktoria, Wawrzinek, Robert, Rademacher, Christoph, Snyder, Nicole L., Elling, Lothar, Hartmann, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069326/ https://www.ncbi.nlm.nih.gov/pubmed/35530592 http://dx.doi.org/10.1039/c9ra05497a

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