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Integrated Design of a Membrane‐Lytic Peptide‐Based Intravenous Nanotherapeutic Suppresses Triple‐Negative Breast Cancer

Membrane‐lytic peptides offer broad synthetic flexibilities and design potential to the arsenal of anticancer therapeutics, which can be limited by cytotoxicity to noncancerous cells and induction of drug resistance via stress‐induced mutagenesis. Despite continued research efforts on membrane‐perfo...

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Detalles Bibliográficos
Autores principales: Chen, Charles H., Liu, Yu‐Han, Eskandari, Arvin, Ghimire, Jenisha, Lin, Leon Chien‐Wei, Fang, Zih‐Syun, Wimley, William C., Ulmschneider, Jakob P., Suntharalingam, Kogularamanan, Hu, Che‐Ming Jack, Ulmschneider, Martin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069370/
https://www.ncbi.nlm.nih.gov/pubmed/35246961
http://dx.doi.org/10.1002/advs.202105506