Cargando…
Integrated Design of a Membrane‐Lytic Peptide‐Based Intravenous Nanotherapeutic Suppresses Triple‐Negative Breast Cancer
Membrane‐lytic peptides offer broad synthetic flexibilities and design potential to the arsenal of anticancer therapeutics, which can be limited by cytotoxicity to noncancerous cells and induction of drug resistance via stress‐induced mutagenesis. Despite continued research efforts on membrane‐perfo...
Autores principales: | Chen, Charles H., Liu, Yu‐Han, Eskandari, Arvin, Ghimire, Jenisha, Lin, Leon Chien‐Wei, Fang, Zih‐Syun, Wimley, William C., Ulmschneider, Jakob P., Suntharalingam, Kogularamanan, Hu, Che‐Ming Jack, Ulmschneider, Martin B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069370/ https://www.ncbi.nlm.nih.gov/pubmed/35246961 http://dx.doi.org/10.1002/advs.202105506 |
Ejemplares similares
-
A reactive oxygen species-generating, cancer stem cell-potent manganese(ii) complex and its encapsulation into polymeric nanoparticles
por: Eskandari, Arvin, et al.
Publicado: (2019) -
Determining Peptide Partitioning Properties via Computer Simulation
por: Ulmschneider, Jakob P., et al.
Publicado: (2010) -
Modulating the Chemical and Biological Properties of Cancer Stem Cell-Potent Copper(II)-Nonsteroidal Anti-Inflammatory Drug Complexes
por: Shin, Jimin, et al.
Publicado: (2019) -
Spontaneous formation of structurally diverse membrane channel architectures from a single antimicrobial peptide
por: Wang, Yukun, et al.
Publicado: (2016) -
Polypyridyl Zinc(II)-Indomethacin Complexes with Potent Anti-Breast Cancer Stem Cell Activity
por: Rundstadler, Tiffany K., et al.
Publicado: (2018)