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Ruscogenin alleviates LPS-triggered pulmonary endothelial barrier dysfunction through targeting NMMHC IIA to modulate TLR4 signaling

Pulmonary endothelial barrier dysfunction is a hallmark of clinical pulmonary edema and contributes to the development of acute lung injury (ALI). Here we reported that ruscogenin (RUS), an effective steroidal sapogenin of Radix Ophiopogon japonicus, attenuated lipopolysaccharides (LPS)-induced pulm...

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Detalles Bibliográficos
Autores principales:	Wu, Yunhao, Yu, Xiu, Wang, Yuwei, Huang, Yalin, Tang, Jiahui, Gong, Shuaishuai, Jiang, Siyu, Xia, Yuanli, Li, Fang, Yu, Boyang, Zhang, Yuanyuan, Kou, Junping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069402/ https://www.ncbi.nlm.nih.gov/pubmed/35530141 http://dx.doi.org/10.1016/j.apsb.2021.09.017

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