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The generation of PD-L1 and PD-L2 in cancer cells: From nuclear chromatin reorganization to extracellular presentation

The immune checkpoint blockade (ICB) targeting on PD-1/PD-L1 has shown remarkable promise in treating cancers. However, the low response rate and frequently observed severe side effects limit its broad benefits. It is partially due to less understanding of the biological regulation of PD-L1. Here, w...

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Detalles Bibliográficos
Autores principales:	Fan, Zhiwei, Wu, Changyue, Chen, Miaomiao, Jiang, Yongying, Wu, Yuanyuan, Mao, Renfang, Fan, Yihui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069407/ https://www.ncbi.nlm.nih.gov/pubmed/35530130 http://dx.doi.org/10.1016/j.apsb.2021.09.010

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