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Crystal structure of 4-bromo-N-(propyl­carbamo­yl)benzene­sulfonamide

The title compound, C(10)H(13)BrN(2)O(3)S, 1, contains a sulfonyl urea moiety, which possesses potential therapeutic functions (e.g., anti-diabetic and herbicidal). The geometry of 1 is similar to its closely related analogues, chlorpropamide and tolbutamide. This compound crystallizes in the monocl...

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Detalles Bibliográficos
Autores principales: Bookwala, Mustafa, Patel, Saloni, Flaherty, Patrick T., Wildfong, Peter L. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069509/
https://www.ncbi.nlm.nih.gov/pubmed/35547791
http://dx.doi.org/10.1107/S2056989022003723
Descripción
Sumario:The title compound, C(10)H(13)BrN(2)O(3)S, 1, contains a sulfonyl urea moiety, which possesses potential therapeutic functions (e.g., anti-diabetic and herbicidal). The geometry of 1 is similar to its closely related analogues, chlorpropamide and tolbutamide. This compound crystallizes in the monoclinic space group C2/c, having one mol­ecule in its asymmetric unit. The crystal structure of 1, recorded at 296 K, shows inter­molecular N—H⋯O and C—H⋯O-type infinite hydrogen-bonded chains involving the sulfonyl urea moiety. Hirshfeld surface analysis and the two-dimensional fingerprint plots confirmed hydrogen bonding as the dominant feature in the crystal packing.