Crystal structure of 4-bromo-N-(propyl­carbamo­yl)benzene­sulfonamide

The title compound, C(10)H(13)BrN(2)O(3)S, 1, contains a sulfonyl urea moiety, which possesses potential therapeutic functions (e.g., anti-diabetic and herbicidal). The geometry of 1 is similar to its closely related analogues, chlorpropamide and tolbutamide. This compound crystallizes in the monocl...

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Autores principales: Bookwala, Mustafa, Patel, Saloni, Flaherty, Patrick T., Wildfong, Peter L. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069509/
https://www.ncbi.nlm.nih.gov/pubmed/35547791
http://dx.doi.org/10.1107/S2056989022003723
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author Bookwala, Mustafa
Patel, Saloni
Flaherty, Patrick T.
Wildfong, Peter L. D.
author_facet Bookwala, Mustafa
Patel, Saloni
Flaherty, Patrick T.
Wildfong, Peter L. D.
author_sort Bookwala, Mustafa
collection PubMed
description The title compound, C(10)H(13)BrN(2)O(3)S, 1, contains a sulfonyl urea moiety, which possesses potential therapeutic functions (e.g., anti-diabetic and herbicidal). The geometry of 1 is similar to its closely related analogues, chlorpropamide and tolbutamide. This compound crystallizes in the monoclinic space group C2/c, having one mol­ecule in its asymmetric unit. The crystal structure of 1, recorded at 296 K, shows inter­molecular N—H⋯O and C—H⋯O-type infinite hydrogen-bonded chains involving the sulfonyl urea moiety. Hirshfeld surface analysis and the two-dimensional fingerprint plots confirmed hydrogen bonding as the dominant feature in the crystal packing.
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spelling pubmed-90695092022-05-10 Crystal structure of 4-bromo-N-(propyl­carbamo­yl)benzene­sulfonamide Bookwala, Mustafa Patel, Saloni Flaherty, Patrick T. Wildfong, Peter L. D. Acta Crystallogr E Crystallogr Commun Research Communications The title compound, C(10)H(13)BrN(2)O(3)S, 1, contains a sulfonyl urea moiety, which possesses potential therapeutic functions (e.g., anti-diabetic and herbicidal). The geometry of 1 is similar to its closely related analogues, chlorpropamide and tolbutamide. This compound crystallizes in the monoclinic space group C2/c, having one mol­ecule in its asymmetric unit. The crystal structure of 1, recorded at 296 K, shows inter­molecular N—H⋯O and C—H⋯O-type infinite hydrogen-bonded chains involving the sulfonyl urea moiety. Hirshfeld surface analysis and the two-dimensional fingerprint plots confirmed hydrogen bonding as the dominant feature in the crystal packing. International Union of Crystallography 2022-04-07 /pmc/articles/PMC9069509/ /pubmed/35547791 http://dx.doi.org/10.1107/S2056989022003723 Text en © Bookwala et al. 2022 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Research Communications
Bookwala, Mustafa
Patel, Saloni
Flaherty, Patrick T.
Wildfong, Peter L. D.
Crystal structure of 4-bromo-N-(propyl­carbamo­yl)benzene­sulfonamide
title Crystal structure of 4-bromo-N-(propyl­carbamo­yl)benzene­sulfonamide
title_full Crystal structure of 4-bromo-N-(propyl­carbamo­yl)benzene­sulfonamide
title_fullStr Crystal structure of 4-bromo-N-(propyl­carbamo­yl)benzene­sulfonamide
title_full_unstemmed Crystal structure of 4-bromo-N-(propyl­carbamo­yl)benzene­sulfonamide
title_short Crystal structure of 4-bromo-N-(propyl­carbamo­yl)benzene­sulfonamide
title_sort crystal structure of 4-bromo-n-(propyl­carbamo­yl)benzene­sulfonamide
topic Research Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069509/
https://www.ncbi.nlm.nih.gov/pubmed/35547791
http://dx.doi.org/10.1107/S2056989022003723
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