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Safety and efficacy of a feed additive consisting of 6‐phytase (produced by Komagataella phaffii DSM 23036) (OptiPhos(®)) for poultry for fattening, chickens reared for laying, laying hens, turkeys reared for breeding, weaned piglets, pigs for fattening and sows for the renewal of their authorisation and for the new use in breeding hens and turkeys, ornamental birds, suckling piglets and minor pig species for fattening and breeding (Huvepharma EOOd)

OptiPhos(®) is the trade name of the feed additive under assessment containing 6‐phytase produced by a genetically modified strain of Komagataella phaffii. It is authorised for use in chickens for fattening and reared for laying, turkeys for fattening and reared for breeding, other avian species for...

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Autores principales: Bampidis, Vasileios, Azimonti, Giovanna, Bastos, Maria de Lourdes, Christensen, Henrik, Dusemund, Birgit, Fašmon Durjava, Mojca, Kouba, Maryline, López‐Alonso, Marta, López Puente, Secundino, Marcon, Francesca, Mayo, Baltasar, Pechová, Alena, Petkova, Mariana, Ramos, Fernando, Sanz, Yolanda, Villa, Roberto Edoardo, Woutersen, Ruud, Galobart, Jaume, Anguita, Montserrat, Ortuño, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069549/
https://www.ncbi.nlm.nih.gov/pubmed/35540799
http://dx.doi.org/10.2903/j.efsa.2022.7238
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author Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Fašmon Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Galobart, Jaume
Anguita, Montserrat
Ortuño, Jordi
author_facet Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Fašmon Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Galobart, Jaume
Anguita, Montserrat
Ortuño, Jordi
collection PubMed
description OptiPhos(®) is the trade name of the feed additive under assessment containing 6‐phytase produced by a genetically modified strain of Komagataella phaffii. It is authorised for use in chickens for fattening and reared for laying, turkeys for fattening and reared for breeding, other avian species for fattening, laying hens, weaned piglets, pigs for fattening and sows. This scientific opinion concerns the request for the renewal of the authorisation of the additive for the species/categories for which there is an authorisation and the extension of use to breeding hens, turkeys for breeding purposes, ornamental birds, minor pig species for fattening or breeding and suckling piglets for the period when solid feed is given. The applicant provided evidence that the additive currently in the market complies with the conditions of the authorisation. There is no new evidence that would lead the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) to reconsider previous conclusions that the additive remains safe for the animal species/categories, the consumer and the environment under the authorised conditions of use. This conclusion applies also to the new target species/categories for which a request of extension of use is made. The additive is not irritant to skin or eyes but should be considered a respiratory sensitiser. There was no need for assessing the efficacy of the additive for the authorised species/categories. The additive has the potential to be efficacious at 125 OTU/kg complete feed in all poultry species other than turkeys, ornamental birds, pigs for fattening, sows and minor pig species for fattening or breeding; and in turkeys for fattening, reared for breeding and for breeding purposes, weaned piglets and suckling piglets (for the period when solid feed is given) at 250 OTU/kg feed.
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spelling pubmed-90695492022-05-09 Safety and efficacy of a feed additive consisting of 6‐phytase (produced by Komagataella phaffii DSM 23036) (OptiPhos(®)) for poultry for fattening, chickens reared for laying, laying hens, turkeys reared for breeding, weaned piglets, pigs for fattening and sows for the renewal of their authorisation and for the new use in breeding hens and turkeys, ornamental birds, suckling piglets and minor pig species for fattening and breeding (Huvepharma EOOd) Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Fašmon Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Galobart, Jaume Anguita, Montserrat Ortuño, Jordi EFSA J Scientific Opinion OptiPhos(®) is the trade name of the feed additive under assessment containing 6‐phytase produced by a genetically modified strain of Komagataella phaffii. It is authorised for use in chickens for fattening and reared for laying, turkeys for fattening and reared for breeding, other avian species for fattening, laying hens, weaned piglets, pigs for fattening and sows. This scientific opinion concerns the request for the renewal of the authorisation of the additive for the species/categories for which there is an authorisation and the extension of use to breeding hens, turkeys for breeding purposes, ornamental birds, minor pig species for fattening or breeding and suckling piglets for the period when solid feed is given. The applicant provided evidence that the additive currently in the market complies with the conditions of the authorisation. There is no new evidence that would lead the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) to reconsider previous conclusions that the additive remains safe for the animal species/categories, the consumer and the environment under the authorised conditions of use. This conclusion applies also to the new target species/categories for which a request of extension of use is made. The additive is not irritant to skin or eyes but should be considered a respiratory sensitiser. There was no need for assessing the efficacy of the additive for the authorised species/categories. The additive has the potential to be efficacious at 125 OTU/kg complete feed in all poultry species other than turkeys, ornamental birds, pigs for fattening, sows and minor pig species for fattening or breeding; and in turkeys for fattening, reared for breeding and for breeding purposes, weaned piglets and suckling piglets (for the period when solid feed is given) at 250 OTU/kg feed. John Wiley and Sons Inc. 2022-05-05 /pmc/articles/PMC9069549/ /pubmed/35540799 http://dx.doi.org/10.2903/j.efsa.2022.7238 Text en © 2022 Wiley‐VCH Verlag GmbH & Co. KgaA on behalf of the European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Fašmon Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Galobart, Jaume
Anguita, Montserrat
Ortuño, Jordi
Safety and efficacy of a feed additive consisting of 6‐phytase (produced by Komagataella phaffii DSM 23036) (OptiPhos(®)) for poultry for fattening, chickens reared for laying, laying hens, turkeys reared for breeding, weaned piglets, pigs for fattening and sows for the renewal of their authorisation and for the new use in breeding hens and turkeys, ornamental birds, suckling piglets and minor pig species for fattening and breeding (Huvepharma EOOd)
title Safety and efficacy of a feed additive consisting of 6‐phytase (produced by Komagataella phaffii DSM 23036) (OptiPhos(®)) for poultry for fattening, chickens reared for laying, laying hens, turkeys reared for breeding, weaned piglets, pigs for fattening and sows for the renewal of their authorisation and for the new use in breeding hens and turkeys, ornamental birds, suckling piglets and minor pig species for fattening and breeding (Huvepharma EOOd)
title_full Safety and efficacy of a feed additive consisting of 6‐phytase (produced by Komagataella phaffii DSM 23036) (OptiPhos(®)) for poultry for fattening, chickens reared for laying, laying hens, turkeys reared for breeding, weaned piglets, pigs for fattening and sows for the renewal of their authorisation and for the new use in breeding hens and turkeys, ornamental birds, suckling piglets and minor pig species for fattening and breeding (Huvepharma EOOd)
title_fullStr Safety and efficacy of a feed additive consisting of 6‐phytase (produced by Komagataella phaffii DSM 23036) (OptiPhos(®)) for poultry for fattening, chickens reared for laying, laying hens, turkeys reared for breeding, weaned piglets, pigs for fattening and sows for the renewal of their authorisation and for the new use in breeding hens and turkeys, ornamental birds, suckling piglets and minor pig species for fattening and breeding (Huvepharma EOOd)
title_full_unstemmed Safety and efficacy of a feed additive consisting of 6‐phytase (produced by Komagataella phaffii DSM 23036) (OptiPhos(®)) for poultry for fattening, chickens reared for laying, laying hens, turkeys reared for breeding, weaned piglets, pigs for fattening and sows for the renewal of their authorisation and for the new use in breeding hens and turkeys, ornamental birds, suckling piglets and minor pig species for fattening and breeding (Huvepharma EOOd)
title_short Safety and efficacy of a feed additive consisting of 6‐phytase (produced by Komagataella phaffii DSM 23036) (OptiPhos(®)) for poultry for fattening, chickens reared for laying, laying hens, turkeys reared for breeding, weaned piglets, pigs for fattening and sows for the renewal of their authorisation and for the new use in breeding hens and turkeys, ornamental birds, suckling piglets and minor pig species for fattening and breeding (Huvepharma EOOd)
title_sort safety and efficacy of a feed additive consisting of 6‐phytase (produced by komagataella phaffii dsm 23036) (optiphos(®)) for poultry for fattening, chickens reared for laying, laying hens, turkeys reared for breeding, weaned piglets, pigs for fattening and sows for the renewal of their authorisation and for the new use in breeding hens and turkeys, ornamental birds, suckling piglets and minor pig species for fattening and breeding (huvepharma eood)
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069549/
https://www.ncbi.nlm.nih.gov/pubmed/35540799
http://dx.doi.org/10.2903/j.efsa.2022.7238
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AT christensenhenrik safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT dusemundbirgit safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT fasmondurjavamojca safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT koubamaryline safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT lopezalonsomarta safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT lopezpuentesecundino safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT marconfrancesca safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT mayobaltasar safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT pechovaalena safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT petkovamariana safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT ramosfernando safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT sanzyolanda safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT villarobertoedoardo safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT woutersenruud safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT galobartjaume safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT anguitamontserrat safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen
AT ortunojordi safetyandefficacyofafeedadditiveconsistingof6phytaseproducedbykomagataellaphaffiidsm23036optiphosforpoultryforfatteningchickensrearedforlayinglayinghensturkeysrearedforbreedingweanedpigletspigsforfatteningandsowsfortherenewaloftheirauthorisationandforthen