Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer

The androgen receptor (AR) is a prostate master transcription factor. It binds to genetic enhancers, where it regulates gene activity and plays a fundamental role in prostate pathophysiology. Previous work has demonstrated that AR-DNA binding is systematically and consistently reprogrammed during pr...

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Detalles Bibliográficos
Autores principales: Severson, Tesa, Qiu, Xintao, Alshalalfa, Mohammed, Sjöström, Martin, Quigley, David, Bergman, Andries, Long, Henry, Feng, Felix, Freedman, Matthew L., Zwart, Wilbert, Pomerantz, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069737/
https://www.ncbi.nlm.nih.gov/pubmed/35509021
http://dx.doi.org/10.1186/s13148-022-01278-8

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