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scSemiAE: a deep model with semi-supervised learning for single-cell transcriptomics

BACKGROUND: With the development of modern sequencing technology, hundreds of thousands of single-cell RNA-sequencing (scRNA-seq) profiles allow to explore the heterogeneity in the cell level, but it faces the challenges of high dimensions and high sparsity. Dimensionality reduction is essential for...

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Detalles Bibliográficos
Autores principales: Dong, Jiayi, Zhang, Yin, Wang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069784/
https://www.ncbi.nlm.nih.gov/pubmed/35513780
http://dx.doi.org/10.1186/s12859-022-04703-0