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A novel approach to predicting the synergy of anti-cancer drug combinations using document-based feature extraction

BACKGROUND: To reduce drug side effects and enhance their therapeutic effect compared with single drugs, drug combination research, combining two or more drugs, is highly important. Conducting in-vivo and in-vitro experiments on a vast number of drug combinations incurs astronomical time and cost. T...

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Detalles Bibliográficos
Autores principales: Shim, Yongsun, Lee, Munhwan, Kim, Pil-Jong, Kim, Hong-Gee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069794/
https://www.ncbi.nlm.nih.gov/pubmed/35513784
http://dx.doi.org/10.1186/s12859-022-04698-8