Diminished Immune Surveillance during Histologic Progression of Intraductal Papillary Mucinous Neoplasms Offers a Therapeutic Opportunity for Cancer Interception

PURPOSE: Intraductal papillary mucinous neoplasms (IPMN) are bona fide precursors to pancreatic ductal adenocarcinoma (PDAC). While genomic alterations during multistep IPMN progression have been well cataloged, the accompanying changes within the tumor immune microenvironment (TIME) have not been c...

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Detalles Bibliográficos
Autores principales: Hernandez, Sharia, Parra, Edwin Roger, Uraoka, Naohiro, Tang, Ximing, Shen, Yu, Qiao, Wei, Jiang, Mei, Zhang, Shanyu, Mino, Barbara, Lu, Wei, Pandurengan, Renganayaki, Haymaker, Cara, Affolter, Kajsa, Scaife, Courtney L., Yip-Schneider, Michele, Schmidt, C. Max, Firpo, Matthew A., Mulvihill, Sean J., Koay, Eugene J., Wang, Huamin, Wistuba, Ignacio I., Maitra, Anirban, Solis, Luisa M., Sen, Subrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069801/
https://www.ncbi.nlm.nih.gov/pubmed/35491652
http://dx.doi.org/10.1158/1078-0432.CCR-21-2585

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