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Methods for direct C(sp(2))–H bonds azidation

Direct functionalization of C–H bonds has attracted great attention in recent years from the perspectives of atom and step economy. In this context, a variety of processes have been developed for the construction of synthetically and biologically important organic azides through the oxidative C–H bo...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Ebadi, Abdol Ghaffar, Youseftabar-Miri, Leila, Hassanpour, Akbar, Vessally, Esmail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069887/
https://www.ncbi.nlm.nih.gov/pubmed/35528700
http://dx.doi.org/10.1039/c9ra04534a
Descripción
Sumario:Direct functionalization of C–H bonds has attracted great attention in recent years from the perspectives of atom and step economy. In this context, a variety of processes have been developed for the construction of synthetically and biologically important organic azides through the oxidative C–H bonds azidation. In this review, we have summarized recent progress in the direct azidation of C(sp(2))–H bonds. The review is divided into three major sections: (i) direct azidation of aromatic C–H bonds; (ii) direct azidation of olefinic C–H bonds; and (iii) direct azidation of aldehydic C–H bonds. Mechanistic aspects of the reactions are considered and discussed in detail.