Cargando…
Effectiveness of Topical 0.5% Ivermectin Shampoo in the Treatment of Pediculosis Capitis among School-going Female Children
BACKGROUND: Pediculosis is a common ectoparasitic infestation in children. There are different treatment modalities that have been used in the treatment of pediculosis capitis from time immemorial, each with their own shortcomings. Increasing emergence of resistance to permethrin has led to the look...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069911/ https://www.ncbi.nlm.nih.gov/pubmed/35531485 http://dx.doi.org/10.4103/ijt.ijt_157_20 |
_version_ | 1784700530255200256 |
---|---|
author | Karthikeyan, Kaliaperumal Aishwarya, Manju Elayaperumal, Suguna |
author_facet | Karthikeyan, Kaliaperumal Aishwarya, Manju Elayaperumal, Suguna |
author_sort | Karthikeyan, Kaliaperumal |
collection | PubMed |
description | BACKGROUND: Pediculosis is a common ectoparasitic infestation in children. There are different treatment modalities that have been used in the treatment of pediculosis capitis from time immemorial, each with their own shortcomings. Increasing emergence of resistance to permethrin has led to the lookout for newer alternatives. AIMS AND OBJECTIVES: The role of topical ivermectin in the management of pediculosis in people with culturally different hair grooming practices is analyzed in this study. MATERIALS AND METHODS: This observational open-label clinical study was conducted in September–November 2019 in the schools that were under the rural health center at South India among school-going female children aged between 13 and 16 years of age and diagnosed with pediculosis. RESULTS: This study demonstrated that a single application of ivermectin shampoo was able to kill head lice in 86.2% of the participants. In participants with persistent infection (13.8%), a repeat application killed the entire louse and 100% efficacy was demonstrated. Topical ivermectin is devoid of systemic side effects of oral ivermectin. Topical ivermectin has found to be more effective than contemporary recommended agents such as malathion and permethrin. |
format | Online Article Text |
id | pubmed-9069911 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-90699112022-05-05 Effectiveness of Topical 0.5% Ivermectin Shampoo in the Treatment of Pediculosis Capitis among School-going Female Children Karthikeyan, Kaliaperumal Aishwarya, Manju Elayaperumal, Suguna Int J Trichology Original Article BACKGROUND: Pediculosis is a common ectoparasitic infestation in children. There are different treatment modalities that have been used in the treatment of pediculosis capitis from time immemorial, each with their own shortcomings. Increasing emergence of resistance to permethrin has led to the lookout for newer alternatives. AIMS AND OBJECTIVES: The role of topical ivermectin in the management of pediculosis in people with culturally different hair grooming practices is analyzed in this study. MATERIALS AND METHODS: This observational open-label clinical study was conducted in September–November 2019 in the schools that were under the rural health center at South India among school-going female children aged between 13 and 16 years of age and diagnosed with pediculosis. RESULTS: This study demonstrated that a single application of ivermectin shampoo was able to kill head lice in 86.2% of the participants. In participants with persistent infection (13.8%), a repeat application killed the entire louse and 100% efficacy was demonstrated. Topical ivermectin is devoid of systemic side effects of oral ivermectin. Topical ivermectin has found to be more effective than contemporary recommended agents such as malathion and permethrin. Wolters Kluwer - Medknow 2022 2022-04-04 /pmc/articles/PMC9069911/ /pubmed/35531485 http://dx.doi.org/10.4103/ijt.ijt_157_20 Text en Copyright: © 2022 International Journal of Trichology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Karthikeyan, Kaliaperumal Aishwarya, Manju Elayaperumal, Suguna Effectiveness of Topical 0.5% Ivermectin Shampoo in the Treatment of Pediculosis Capitis among School-going Female Children |
title | Effectiveness of Topical 0.5% Ivermectin Shampoo in the Treatment of Pediculosis Capitis among School-going Female Children |
title_full | Effectiveness of Topical 0.5% Ivermectin Shampoo in the Treatment of Pediculosis Capitis among School-going Female Children |
title_fullStr | Effectiveness of Topical 0.5% Ivermectin Shampoo in the Treatment of Pediculosis Capitis among School-going Female Children |
title_full_unstemmed | Effectiveness of Topical 0.5% Ivermectin Shampoo in the Treatment of Pediculosis Capitis among School-going Female Children |
title_short | Effectiveness of Topical 0.5% Ivermectin Shampoo in the Treatment of Pediculosis Capitis among School-going Female Children |
title_sort | effectiveness of topical 0.5% ivermectin shampoo in the treatment of pediculosis capitis among school-going female children |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069911/ https://www.ncbi.nlm.nih.gov/pubmed/35531485 http://dx.doi.org/10.4103/ijt.ijt_157_20 |
work_keys_str_mv | AT karthikeyankaliaperumal effectivenessoftopical05ivermectinshampoointhetreatmentofpediculosiscapitisamongschoolgoingfemalechildren AT aishwaryamanju effectivenessoftopical05ivermectinshampoointhetreatmentofpediculosiscapitisamongschoolgoingfemalechildren AT elayaperumalsuguna effectivenessoftopical05ivermectinshampoointhetreatmentofpediculosiscapitisamongschoolgoingfemalechildren |