Xeroderma Pigmentosum Complementation Group C (XPC): Emerging Roles in Non-Dermatologic Malignancies

Xeroderma pigmentosum complementation group C (XPC) is a DNA damage recognition protein essential for initiation of global-genomic nucleotide excision repair (GG-NER). Humans carrying germline mutations in the XPC gene exhibit strong susceptibility to skin cancer due to defective removal via GG-NER...

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Detalles Bibliográficos
Autores principales: Nasrallah, Nawar Al, Wiese, Benjamin M., Sears, Catherine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069926/
https://www.ncbi.nlm.nih.gov/pubmed/35530314
http://dx.doi.org/10.3389/fonc.2022.846965

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