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Recent Progress on Highly Selective and Sensitive Electrochemical Aptamer-based Sensors

Highly selective, sensitive, and stable biosensors are essential for the molecular level understanding of many physiological activities and diseases. Electrochemical aptamer-based (E-AB) sensor is an appealing platform for measurement in biological system, attributing to the combined advantages of h...

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Detalles Bibliográficos
Autores principales: Tang, Tianwei, Liu, Yinghuan, Jiang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jilin University and The Editorial Department of Chemical Research in Chinese Universities 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069955/
https://www.ncbi.nlm.nih.gov/pubmed/35530120
http://dx.doi.org/10.1007/s40242-022-2084-z
Descripción
Sumario:Highly selective, sensitive, and stable biosensors are essential for the molecular level understanding of many physiological activities and diseases. Electrochemical aptamer-based (E-AB) sensor is an appealing platform for measurement in biological system, attributing to the combined advantages of high selectivity of the aptamer and high sensitivity of electrochemical analysis. This review summarizes the latest development of E-AB sensors, focuses on the modification strategies used in the fabrication of sensors and the sensing strategies for analytes of different sizes in biological system, and then looks forward to the challenges and prospects of the future development of electrochemical aptamer-based sensors.