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Seroprevalence and factors associated with SARS-CoV-2 infection among education workers after the first wave: the first cross-sectional study in Brazil

BACKGROUND: The school community was heavily impacted by the Covid-19 pandemic, especially with the long time of school closures. This study aimed to analyze the seroprevalence of SARS-CoV-2 antibodies and possible factors associated with seropositivity for COVID-19 in teachers and other school staf...

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Autores principales: França, Pâmela de Castro, Silva, Paulo Goberlânio Barros, Rocha, Jose Lima de Carvalho, Perdigão, Anne Carolinne Bezerra, de Oliveira, Nayara Santos, Araújo, Fernanda Montenegro de Carvalho, Fonseca, Marcela Helena Gambim, Lima, Giovanna Rolim Pinheiro, de Almeida, Magda Moura, Alencar, Carlos Henrique, de Oliveira, Wanderson Kleber, Cavalcanti, Luciano Pamplona de Góes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070070/
https://www.ncbi.nlm.nih.gov/pubmed/35522813
http://dx.doi.org/10.1590/0037-8682-0606-2021
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author França, Pâmela de Castro
Silva, Paulo Goberlânio Barros
Rocha, Jose Lima de Carvalho
Perdigão, Anne Carolinne Bezerra
de Oliveira, Nayara Santos
Araújo, Fernanda Montenegro de Carvalho
Fonseca, Marcela Helena Gambim
Lima, Giovanna Rolim Pinheiro
de Almeida, Magda Moura
Alencar, Carlos Henrique
de Oliveira, Wanderson Kleber
Cavalcanti, Luciano Pamplona de Góes
author_facet França, Pâmela de Castro
Silva, Paulo Goberlânio Barros
Rocha, Jose Lima de Carvalho
Perdigão, Anne Carolinne Bezerra
de Oliveira, Nayara Santos
Araújo, Fernanda Montenegro de Carvalho
Fonseca, Marcela Helena Gambim
Lima, Giovanna Rolim Pinheiro
de Almeida, Magda Moura
Alencar, Carlos Henrique
de Oliveira, Wanderson Kleber
Cavalcanti, Luciano Pamplona de Góes
author_sort França, Pâmela de Castro
collection PubMed
description BACKGROUND: The school community was heavily impacted by the Covid-19 pandemic, especially with the long time of school closures. This study aimed to analyze the seroprevalence of SARS-CoV-2 antibodies and possible factors associated with seropositivity for COVID-19 in teachers and other school staff, and to estimate the fraction of asymptomatic individuals by sex and age group. METHODS: We conducted a serological survey of SARS-CoV-2 infections. An analytical cross-sectional study was conducted in Fortaleza, Brazil. Teachers and other staff members from pre-schools to universities of higher education to were investigated. RESULTS: A total of 1,901 professionals participated in the study, of which 1,021 were staff and 880 were teachers. The seroprevalence of SARS-CoV-2 was 8.0% (152/1901). In the seropositive group, 48.3% were asymptomatic. There was a predominance of women (68.4%); and, 47.1% of the participants were between 31 and 45 years old. There was an increase in prevalence with increasing age. An inverse relationship was found for education level: more professionals with less education tested positive for COVID-19. The presence of an infected person living in the same household was significantly associated with positive results for COVID-19 among the professionals. CONCLUSIONS: This is the first study to report the seroprevalence of IgG against SARS-CoV-2 in Brazilian educational staff after the first wave of the disease. In this study, the seroprevalence was much lower than that in the general population. During school reopening, a small fraction of school workers showed serologically detectable signs of SARS-CoV-2 exposure.
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spelling pubmed-90700702022-05-13 Seroprevalence and factors associated with SARS-CoV-2 infection among education workers after the first wave: the first cross-sectional study in Brazil França, Pâmela de Castro Silva, Paulo Goberlânio Barros Rocha, Jose Lima de Carvalho Perdigão, Anne Carolinne Bezerra de Oliveira, Nayara Santos Araújo, Fernanda Montenegro de Carvalho Fonseca, Marcela Helena Gambim Lima, Giovanna Rolim Pinheiro de Almeida, Magda Moura Alencar, Carlos Henrique de Oliveira, Wanderson Kleber Cavalcanti, Luciano Pamplona de Góes Rev Soc Bras Med Trop Major Article BACKGROUND: The school community was heavily impacted by the Covid-19 pandemic, especially with the long time of school closures. This study aimed to analyze the seroprevalence of SARS-CoV-2 antibodies and possible factors associated with seropositivity for COVID-19 in teachers and other school staff, and to estimate the fraction of asymptomatic individuals by sex and age group. METHODS: We conducted a serological survey of SARS-CoV-2 infections. An analytical cross-sectional study was conducted in Fortaleza, Brazil. Teachers and other staff members from pre-schools to universities of higher education to were investigated. RESULTS: A total of 1,901 professionals participated in the study, of which 1,021 were staff and 880 were teachers. The seroprevalence of SARS-CoV-2 was 8.0% (152/1901). In the seropositive group, 48.3% were asymptomatic. There was a predominance of women (68.4%); and, 47.1% of the participants were between 31 and 45 years old. There was an increase in prevalence with increasing age. An inverse relationship was found for education level: more professionals with less education tested positive for COVID-19. The presence of an infected person living in the same household was significantly associated with positive results for COVID-19 among the professionals. CONCLUSIONS: This is the first study to report the seroprevalence of IgG against SARS-CoV-2 in Brazilian educational staff after the first wave of the disease. In this study, the seroprevalence was much lower than that in the general population. During school reopening, a small fraction of school workers showed serologically detectable signs of SARS-CoV-2 exposure. Sociedade Brasileira de Medicina Tropical - SBMT 2022-04-29 /pmc/articles/PMC9070070/ /pubmed/35522813 http://dx.doi.org/10.1590/0037-8682-0606-2021 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Major Article
França, Pâmela de Castro
Silva, Paulo Goberlânio Barros
Rocha, Jose Lima de Carvalho
Perdigão, Anne Carolinne Bezerra
de Oliveira, Nayara Santos
Araújo, Fernanda Montenegro de Carvalho
Fonseca, Marcela Helena Gambim
Lima, Giovanna Rolim Pinheiro
de Almeida, Magda Moura
Alencar, Carlos Henrique
de Oliveira, Wanderson Kleber
Cavalcanti, Luciano Pamplona de Góes
Seroprevalence and factors associated with SARS-CoV-2 infection among education workers after the first wave: the first cross-sectional study in Brazil
title Seroprevalence and factors associated with SARS-CoV-2 infection among education workers after the first wave: the first cross-sectional study in Brazil
title_full Seroprevalence and factors associated with SARS-CoV-2 infection among education workers after the first wave: the first cross-sectional study in Brazil
title_fullStr Seroprevalence and factors associated with SARS-CoV-2 infection among education workers after the first wave: the first cross-sectional study in Brazil
title_full_unstemmed Seroprevalence and factors associated with SARS-CoV-2 infection among education workers after the first wave: the first cross-sectional study in Brazil
title_short Seroprevalence and factors associated with SARS-CoV-2 infection among education workers after the first wave: the first cross-sectional study in Brazil
title_sort seroprevalence and factors associated with sars-cov-2 infection among education workers after the first wave: the first cross-sectional study in brazil
topic Major Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070070/
https://www.ncbi.nlm.nih.gov/pubmed/35522813
http://dx.doi.org/10.1590/0037-8682-0606-2021
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