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Distinct Dibasic Cleavage Specificities of Neuropeptide-Producing Cathepsin L and Cathepsin V Cysteine Proteases Compared to PC1/3 and PC2 Serine Proteases

[Image: see text] Neuropeptides, functioning as peptide neurotransmitters and hormones, are generated from proneuropeptide precursors by proteolytic processing at dibasic residue sites (i.e., KR, RK, KK, RR). The cysteine proteases cathepsin L and cathepsin V, combined with the serine proteases prop...

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Detalles Bibliográficos
Autores principales:	Yoon, Michael C., Ames, Janneca, Mosier, Charles, Jiang, Zhenze, Podvin, Sonia, O’Donoghue, Anthony J., Hook, Vivian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070308/ https://www.ncbi.nlm.nih.gov/pubmed/34986304 http://dx.doi.org/10.1021/acschemneuro.1c00653

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