Ramified derivatives of 5-(perylen-3-ylethynyl)uracil-1-acetic acid and their antiviral properties

The propargylamide of N3-Pom-protected 5-(perylen-3-ylethynyl)uracil acetic acid, a universal precursor, was used in a CuAAC click reaction for the synthesis of several derivatives, including three ramified molecules with high activities against tick-borne encephalitis virus (TBEV). Pentaerythritol-...

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Detalles Bibliográficos
Autores principales: Sapozhnikova, Ksenia A., Slesarchuk, Nikita A., Orlov, Alexey A., Khvatov, Evgeny V., Radchenko, Eugene V., Chistov, Alexey A., Ustinov, Alexey V., Palyulin, Vladimir A., Kozlovskaya, Liubov I., Osolodkin, Dmitry I., Korshun, Vladimir A., Brylev, Vladimir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070374/
https://www.ncbi.nlm.nih.gov/pubmed/35531032
http://dx.doi.org/10.1039/c9ra06313g

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