Cargando…

Baseline Plasma Gas6 Protein Elevation Predicts Adverse Outcomes in Hospitalized COVID-19 Patients

Reliable biomarkers allowing early patients' stratification for the risk of adverse outcomes in COVID-19 are lacking. Gas6, together with its tyrosine kinase receptors named TAM, is involved in the regulation of immune homeostasis, fibrosis, and thrombosis. Our aim was to evaluate whether Gas6,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tonello, Stelvio, Rizzi, Manuela, Matino, Erica, Costanzo, Martina, Casciaro, Giuseppe Francesco, Croce, Alessandro, Rizzi, Eleonora, Zecca, Erika, Pedrinelli, Anita, Vassia, Veronica, Landi, Raffaella, Bellan, Mattia, Castello, Luigi Mario, Minisini, Rosalba, Mallela, Venkata Ramana, D'Onghia, Davide, Avanzi, Gian Carlo, Pirisi, Mario, Lilleri, Daniele, Sainaghi, Pier Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070408/ https://www.ncbi.nlm.nih.gov/pubmed/35531477 http://dx.doi.org/10.1155/2022/1568352

Ejemplares similares

Prognostic Markers in Hospitalized COVID-19 Patients: The Role of IP-10 and C-Reactive Protein
por: Rizzi, Manuela, et al.
Publicado: (2022)

CGRP Plasma Levels Correlate with the Clinical Evolution and Prognosis of Hospitalized Acute COVID-19 Patients
por: Rizzi, Manuela, et al.
Publicado: (2022)

Baseline Plasma Osteopontin Protein Elevation Predicts Adverse Outcomes in Hospitalized COVID-19 Patients
por: Tonello, Stelvio, et al.
Publicado: (2023)

Ongoing Mycophenolate Treatment Impairs Anti-SARS-CoV-2 Vaccination Response in Patients Affected by Chronic Inflammatory Autoimmune Diseases or Liver Transplantation Recipients: Results of the RIVALSA Prospective Cohort
por: Zecca, Erika, et al.
Publicado: (2022)

COVID-19 Biomarkers at the Crossroad between Patient Stratification and Targeted Therapy: The Role of Validated and Proposed Parameters
por: Rizzi, Manuela, et al.
Publicado: (2023)

SARS-CoV-2 infection risk is higher in vaccinated patients with inflammatory autoimmune diseases or liver transplantation treated with mycophenolate due to an impaired antiviral immune response: results of the extended follow up of the RIVALSA prospective cohort
por: Rizzi, Manuela, et al.
Publicado: (2023)

Gas6/TAM Axis Involvement in Modulating Inflammation and Fibrosis in COVID-19 Patients
por: Rizzi, Manuela, et al.
Publicado: (2023)

Plasma Pattern of Extracellular Vesicles Isolated from Hepatitis C Virus Patients and Their Effects on Human Vascular Endothelial Cells
por: Grossini, Elena, et al.
Publicado: (2023)

Understanding protection from SARS-CoV-2 using metabolomics
por: Barberis, Elettra, et al.
Publicado: (2021)

Effect of Lactoferrin on Clinical Outcomes of Hospitalized Patients with COVID-19: The LAC Randomized Clinical Trial
por: Matino, Erica, et al.
Publicado: (2023)

Clinical Relevance of Liver Involvement in the Clinical Course of Systemic Sclerosis
por: Lorena, Maria, et al.
Publicado: (2022)

Role of Osteopontin as a Potential Biomarker of Pulmonary Arterial Hypertension in Patients with Systemic Sclerosis and Other Connective Tissue Diseases (CTDs)
por: Bellan, Mattia, et al.
Publicado: (2021)

Gas6/TAM System: A Key Modulator of the Interplay between Inflammation and Fibrosis
por: Bellan, Mattia, et al.
Publicado: (2019)

Severity of Nonalcoholic Fatty Liver Disease in Type 2 Diabetes Mellitus: Relationship between Nongenetic Factors and PNPLA3/HSD17B13 Polymorphisms
por: Bellan, Mattia, et al.
Publicado: (2019)

Interplay of PNPLA3 and HSD17B13 Variants in Modulating the Risk of Hepatocellular Carcinoma among Hepatitis C Patients
por: De Benedittis, Carla, et al.
Publicado: (2020)

Robust and Persistent B- and T-Cell Responses after COVID-19 in Immunocompetent and Solid Organ Transplant Recipient Patients
por: Zavaglio, Federica, et al.
Publicado: (2021)

Periostin Circulating Levels and Genetic Variants in Patients with Non-Alcoholic Fatty Liver Disease
por: Smirne, Carlo, et al.
Publicado: (2020)

Increased Levels of ICOS and ICOSL Are Associated to Pulmonary Arterial Hypertension in Patients Affected by Connective Tissue Diseases
por: Bellan, Mattia, et al.
Publicado: (2022)

Decreased Gas6 and sAxl Plasma Levels Are Associated with Hair Loss in COVID-19 Survivors
por: Apostolo, Daria, et al.
Publicado: (2023)

Rates of Symptomatic SARS-CoV-2 Infection in Patients With Autoimmune Liver Diseases in Northern Italy: A Telemedicine Study
por: Rigamonti, Cristina, et al.
Publicado: (2020)

A 28-Year-Old Woman with Ascites and Multiple Focal Spleen Lesions
por: Pirovano, Alice, et al.
Publicado: (2019)

Determinants of long COVID among adults hospitalized for SARS-CoV-2 infection: A prospective cohort study
por: Bellan, Mattia, et al.
Publicado: (2022)

Inflammatory and Immune Responses during SARS-CoV-2 Infection in Vaccinated and Non-Vaccinated Pregnant Women and Their Newborns
por: Zelini, Paola, et al.
Publicado: (2023)

The Gas6/TAM System and Multiple Sclerosis
por: Bellan, Mattia, et al.
Publicado: (2016)

Finding the seed of recurrence: Hepatocellular carcinoma circulating tumor cells and their potential to drive the surgical treatment
por: Carissimi, Francesca, et al.
Publicado: (2021)

Comment on “Evaluation of serum interleukin-6 levels in hepatocellular carcinoma patients: a systematic review and meta-analysis”
por: Bellan, Mattia, et al.
Publicado: (2019)

mRNA BNT162b Vaccine Elicited Higher Antibody and CD4(+) T-Cell Responses than Patients with Mild COVID-19
por: Zavaglio, Federica, et al.
Publicado: (2022)

Role of Gas6 and TAM Receptors in the Identification of Cardiopulmonary Involvement in Systemic Sclerosis and Scleroderma Spectrum Disorders
por: Bellan, Mattia, et al.
Publicado: (2020)

Cardiac dysfunction as an early predictor of portal hypertension in chronic hepatitis C
por: Marconi, Cecilia, et al.
Publicado: (2017)

“War to the knife” against thromboinflammation to protect endothelial function of COVID-19 patients
por: Guglielmetti, Gabriele, et al.
Publicado: (2020)

Growth Arrest-Specific Gene 6 Administration Ameliorates Sepsis-Induced Organ Damage in Mice and Reduces ROS Formation In Vitro
por: Salmi, Livia, et al.
Publicado: (2021)

Candidate Biomarkers of Liver Fibrosis: A Concise, Pathophysiology-oriented Review
por: Bellan, Mattia, et al.
Publicado: (2018)

Exposure to Plasma From Non-alcoholic Fatty Liver Disease Patients Affects Hepatocyte Viability, Generates Mitochondrial Dysfunction, and Modulates Pathways Involved in Fat Accumulation and Inflammation
por: Grossini, Elena, et al.
Publicado: (2021)

Gas6/TAM Signaling Components as Novel Biomarkers of Liver Fibrosis
por: Smirne, Carlo, et al.
Publicado: (2019)

New Insights into the Role of Tyro3, Axl, and Mer Receptors in Rheumatoid Arthritis
por: Pagani, Sara, et al.
Publicado: (2020)

Acute decompensated heart failure in the emergency department: Identification of early predictors of outcome
por: Castello, Luigi Mario, et al.
Publicado: (2017)

Interaction between thrombin potential and age on early clinical outcome in patients hospitalized for COVID-19
por: Mennuni, Marco G., et al.
Publicado: (2021)

Liver Stiffness, Not Fat Liver Content, Predicts the Length of QTc Interval in Patients with Chronic Liver Disease
por: Bellan, Mattia, et al.
Publicado: (2019)

Cardiopulmonary Exercise Testing Is an Accurate Tool for the Diagnosis of Pulmonary Arterial Hypertension in Scleroderma Related Diseases
por: Bellan, Mattia, et al.
Publicado: (2021)

Identification of a Functional, CRM-1-Dependent Nuclear Export Signal in Hepatitis C Virus Core Protein
por: Cerutti, Andrea, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_jtk3hi8dtamh6miso56ambfeiu