Cargando…
PPEGMEMA-based cationic copolymers designed for layer-by-layer assembly
We have synthesized three PPEGMEMA-based cationic copolymers with similar amine contents but with systematic variation in the average length of the PEG side chains. The positively charged copolymers were paired with alginate to fabricate layer-by-layer assembled multilayered films. It was demonstrat...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070437/ https://www.ncbi.nlm.nih.gov/pubmed/35528594 http://dx.doi.org/10.1039/c9ra05464b |
_version_ | 1784700639460196352 |
---|---|
author | Jiang, Tao Zajforoushan Moghaddam, Saeed Thormann, Esben |
author_facet | Jiang, Tao Zajforoushan Moghaddam, Saeed Thormann, Esben |
author_sort | Jiang, Tao |
collection | PubMed |
description | We have synthesized three PPEGMEMA-based cationic copolymers with similar amine contents but with systematic variation in the average length of the PEG side chains. The positively charged copolymers were paired with alginate to fabricate layer-by-layer assembled multilayered films. It was demonstrated that the polymeric design, in terms of the systematic variation in the average length of the PEG units, affects the polyelectrolyte multilayer growth mechanism and can be used to tune the structural properties and the water content of the layers. In addition, by partial cross-linking of the amine groups present in the copolymer backbone, disintegration of the film induced by pH changes was prevented. Finally, it was demonstrated how the cross-linked multilayered film can exhibit cationic, zwitterionic and anionic properties depending on the pH value and how these changes are associated with swelling, layer contraction and changes in water content. |
format | Online Article Text |
id | pubmed-9070437 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-90704372022-05-05 PPEGMEMA-based cationic copolymers designed for layer-by-layer assembly Jiang, Tao Zajforoushan Moghaddam, Saeed Thormann, Esben RSC Adv Chemistry We have synthesized three PPEGMEMA-based cationic copolymers with similar amine contents but with systematic variation in the average length of the PEG side chains. The positively charged copolymers were paired with alginate to fabricate layer-by-layer assembled multilayered films. It was demonstrated that the polymeric design, in terms of the systematic variation in the average length of the PEG units, affects the polyelectrolyte multilayer growth mechanism and can be used to tune the structural properties and the water content of the layers. In addition, by partial cross-linking of the amine groups present in the copolymer backbone, disintegration of the film induced by pH changes was prevented. Finally, it was demonstrated how the cross-linked multilayered film can exhibit cationic, zwitterionic and anionic properties depending on the pH value and how these changes are associated with swelling, layer contraction and changes in water content. The Royal Society of Chemistry 2019-08-28 /pmc/articles/PMC9070437/ /pubmed/35528594 http://dx.doi.org/10.1039/c9ra05464b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Jiang, Tao Zajforoushan Moghaddam, Saeed Thormann, Esben PPEGMEMA-based cationic copolymers designed for layer-by-layer assembly |
title | PPEGMEMA-based cationic copolymers designed for layer-by-layer assembly |
title_full | PPEGMEMA-based cationic copolymers designed for layer-by-layer assembly |
title_fullStr | PPEGMEMA-based cationic copolymers designed for layer-by-layer assembly |
title_full_unstemmed | PPEGMEMA-based cationic copolymers designed for layer-by-layer assembly |
title_short | PPEGMEMA-based cationic copolymers designed for layer-by-layer assembly |
title_sort | ppegmema-based cationic copolymers designed for layer-by-layer assembly |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070437/ https://www.ncbi.nlm.nih.gov/pubmed/35528594 http://dx.doi.org/10.1039/c9ra05464b |
work_keys_str_mv | AT jiangtao ppegmemabasedcationiccopolymersdesignedforlayerbylayerassembly AT zajforoushanmoghaddamsaeed ppegmemabasedcationiccopolymersdesignedforlayerbylayerassembly AT thormannesben ppegmemabasedcationiccopolymersdesignedforlayerbylayerassembly |