One-step construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide via a cascade reaction sequence

A concise and versatile method for the construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide has been achieved in DMSO without addition of extra reagents. The present protocol is compatible with various secondary amines and primary amines, and suitable for i...

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Detalles Bibliográficos
Autores principales: Ding, Chaochao, Wang, Shaoli, Sheng, Yaoguang, Dai, Qian, Zhao, Yunjie, Liang, Guang, Song, Zengqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070531/
https://www.ncbi.nlm.nih.gov/pubmed/35528578
http://dx.doi.org/10.1039/c9ra04540f
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author Ding, Chaochao
Wang, Shaoli
Sheng, Yaoguang
Dai, Qian
Zhao, Yunjie
Liang, Guang
Song, Zengqiang
author_facet Ding, Chaochao
Wang, Shaoli
Sheng, Yaoguang
Dai, Qian
Zhao, Yunjie
Liang, Guang
Song, Zengqiang
author_sort Ding, Chaochao
collection PubMed
description A concise and versatile method for the construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide has been achieved in DMSO without addition of extra reagents. The present protocol is compatible with various secondary amines and primary amines, and suitable for intermolecular and intramolecular reactions. Diverse unsymmetrical thioureas and oxazolidinethiones were efficiently obtained in good to excellent yields via a cascade reaction sequence.
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spelling pubmed-90705312022-05-05 One-step construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide via a cascade reaction sequence Ding, Chaochao Wang, Shaoli Sheng, Yaoguang Dai, Qian Zhao, Yunjie Liang, Guang Song, Zengqiang RSC Adv Chemistry A concise and versatile method for the construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide has been achieved in DMSO without addition of extra reagents. The present protocol is compatible with various secondary amines and primary amines, and suitable for intermolecular and intramolecular reactions. Diverse unsymmetrical thioureas and oxazolidinethiones were efficiently obtained in good to excellent yields via a cascade reaction sequence. The Royal Society of Chemistry 2019-08-27 /pmc/articles/PMC9070531/ /pubmed/35528578 http://dx.doi.org/10.1039/c9ra04540f Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Ding, Chaochao
Wang, Shaoli
Sheng, Yaoguang
Dai, Qian
Zhao, Yunjie
Liang, Guang
Song, Zengqiang
One-step construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide via a cascade reaction sequence
title One-step construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide via a cascade reaction sequence
title_full One-step construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide via a cascade reaction sequence
title_fullStr One-step construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide via a cascade reaction sequence
title_full_unstemmed One-step construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide via a cascade reaction sequence
title_short One-step construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide via a cascade reaction sequence
title_sort one-step construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide via a cascade reaction sequence
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070531/
https://www.ncbi.nlm.nih.gov/pubmed/35528578
http://dx.doi.org/10.1039/c9ra04540f
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