Macro-Aspartate Aminotransferase: A Benign Cause of Abnormal Laboratory Findings

Isolated, persistent elevations of aspartate aminotransferase (AST) without plausible explanation may lead to diagnostic confusion. Macro-enzyme aspartate aminotransferase (macro-AST) is an uncommon and benign cause of persistently elevated AST levels in the absence of other diseases. We present a c...

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Detalles Bibliográficos
Autores principales: Reddy, Nikhil, Odish, Fadi S, Agrawal, Sangeeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Gastroenterology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070560/
https://www.ncbi.nlm.nih.gov/pubmed/35530879
http://dx.doi.org/10.7759/cureus.23841
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author Reddy, Nikhil
Odish, Fadi S
Agrawal, Sangeeta
author_facet Reddy, Nikhil
Odish, Fadi S
Agrawal, Sangeeta
author_sort Reddy, Nikhil
collection PubMed
description Isolated, persistent elevations of aspartate aminotransferase (AST) without plausible explanation may lead to diagnostic confusion. Macro-enzyme aspartate aminotransferase (macro-AST) is an uncommon and benign cause of persistently elevated AST levels in the absence of other diseases. We present a case of macro-AST in an otherwise healthy adult male which was confirmed by polyethylene glycol (PEG) precipitation.
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spelling pubmed-90705602022-05-06 Macro-Aspartate Aminotransferase: A Benign Cause of Abnormal Laboratory Findings Reddy, Nikhil Odish, Fadi S Agrawal, Sangeeta Cureus Gastroenterology Isolated, persistent elevations of aspartate aminotransferase (AST) without plausible explanation may lead to diagnostic confusion. Macro-enzyme aspartate aminotransferase (macro-AST) is an uncommon and benign cause of persistently elevated AST levels in the absence of other diseases. We present a case of macro-AST in an otherwise healthy adult male which was confirmed by polyethylene glycol (PEG) precipitation. Cureus 2022-04-05 /pmc/articles/PMC9070560/ /pubmed/35530879 http://dx.doi.org/10.7759/cureus.23841 Text en Copyright © 2022, Reddy et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Reddy, Nikhil
Odish, Fadi S
Agrawal, Sangeeta
Macro-Aspartate Aminotransferase: A Benign Cause of Abnormal Laboratory Findings
title Macro-Aspartate Aminotransferase: A Benign Cause of Abnormal Laboratory Findings
title_full Macro-Aspartate Aminotransferase: A Benign Cause of Abnormal Laboratory Findings
title_fullStr Macro-Aspartate Aminotransferase: A Benign Cause of Abnormal Laboratory Findings
title_full_unstemmed Macro-Aspartate Aminotransferase: A Benign Cause of Abnormal Laboratory Findings
title_short Macro-Aspartate Aminotransferase: A Benign Cause of Abnormal Laboratory Findings
title_sort macro-aspartate aminotransferase: a benign cause of abnormal laboratory findings
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070560/
https://www.ncbi.nlm.nih.gov/pubmed/35530879
http://dx.doi.org/10.7759/cureus.23841
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