Cargando…

Dual targeting of RdRps of SARS-CoV-2 and the mucormycosis-causing fungus: an in silico perspective

During the past few months, mucormycosis has been associated with SARS-CoV-2 infections. Molecular docking combined with molecular dynamics simulation is utilized to test nucleotide-based inhibitors against the RdRps of SARS-CoV-2 solved structure and Rhizopus oryzae RdRp model built in silico. The...

Descripción completa

Detalles Bibliográficos
Autor principal:	Elfiky, Abdo A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Future Medicine Ltd 2022
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070561/ https://www.ncbi.nlm.nih.gov/pubmed/35510477 http://dx.doi.org/10.2217/fmb-2022-0083

Ejemplares similares

Targeting SARS-CoV-2 nonstructural protein 15 endoribonuclease: an in silico perspective
por: Mahmud, Shafi, et al.
Publicado: (2021)

GRP78: A possible relationship of COVID-19 and the mucormycosis; in silico perspective
por: Elgohary, Alaa M., et al.
Publicado: (2021)

Interference of Chaga mushroom terpenoids with the attachment of SARS-CoV-2; in silico perspective
por: Elshemey, Wael M., et al.
Publicado: (2022)

Potential antiviral properties of antiplatelet agents against SARS-CoV-2 infection: an in silico perspective
por: Abosheasha, Mohammed A., et al.
Publicado: (2021)

Recognition through GRP78 is enhanced in the UK, South African, and Brazilian variants of SARS-CoV-2; An in silico perspective
por: Ibrahim, Ibrahim M., et al.
Publicado: (2021)

SARS-CoV-2 Delta Variant is Recognized Through GRP78 Host-Cell Surface Receptor, In Silico Perspective
por: Elfiky, Abdo A., et al.
Publicado: (2022)

Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study
por: Elfiky, Abdo A.
Publicado: (2020)

Host-cell recognition through GRP78 is enhanced in the new UK variant of SARS-CoV-2, in silico
por: Elfiky, Abdo A, et al.
Publicado: (2021)

COVID-19 and Mucormycosis: A Black Fungus Disaster?
por: Chillana, Suchira, et al.
Publicado: (2022)

Novel adenosine derivatives against SARS-CoV-2 RNA-dependent RNA polymerase: an in silico perspective
por: Sonousi, Amr, et al.
Publicado: (2021)

Host-cell recognition through Cs-GRP78 is enhanced in the new Omicron variant of SARS-CoV-2, in silico structural point of view
por: Elfiky, Abdo A, et al.
Publicado: (2022)

The anti-HCV, Sofosbuvir, versus the anti-EBOV Remdesivir against SARS-CoV-2 RNA dependent RNA polymerase in silico
por: Elfiky, Abdo A., et al.
Publicado: (2021)

Repurposing antiviral drugs against the human monkeypox virus DNA-dependent RNA polymerase; in silico perspective
por: Abduljalil, Jameel M., et al.
Publicado: (2022)

Alkaloids and flavonoids from African phytochemicals as potential inhibitors of SARS-Cov-2 RNA-dependent RNA polymerase: an in silico perspective
por: Ogunyemi, Oludare M, et al.
Publicado: (2020)

Mucormycosis (black fungus) infection and misuse of corticosteroids in COVID 19 patients in Syria
por: Mohsen, Aya Yaser, et al.
Publicado: (2022)

Mucormycosis - The deadly fungus – A case report with dental perspective
por: Chakraborty, Rakashree, et al.
Publicado: (2022)

The impact of mucormycosis (black fungus) on SARS-CoV-2-infected patients: at a glance
por: Islam, Md. Rezaul, et al.
Publicado: (2022)

SARS-CoV-2 Spike-Heat Shock Protein A5 (GRP78) Recognition may be Related to the Immersed Human Coronaviruses
por: Elfiky, Abdo A.
Publicado: (2020)

Corrigendum to “Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARSCoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study” [Life Sci. 253 (2020) 117592]
por: Elfiky, Abdo A.
Publicado: (2020)

Arabidopsis dual resistance proteins, both RPS4 and RRS1, are required for resistance to bacterial wilt in transgenic Brassica crops
por: Narusaka, Mari, et al.
Publicado: (2014)

AvrRps4 effector family processing and recognition in lettuce
por: Nguyen, Quang‐Minh, et al.
Publicado: (2022)

Passive sampler phases for pesticides: evaluation of AttractSPE™ SDB-RPS and HLB versus Empore™ SDB-RPS
por: Becker, Benjamin, et al.
Publicado: (2021)

Aging correlates with lower threshold cycle values for RdRP/RdRP+S genes during molecular detection of SARS-CoV-2
por: Mikuła-Pietrasik, Justyna, et al.
Publicado: (2021)

CRISPR-Cas9-Based Mutagenesis of the Mucormycosis-Causing Fungus Lichtheimia corymbifera
por: Ibragimova, Sandugash, et al.
Publicado: (2020)

SARS-CoV-2 spike behavior in situ: a Cryo-EM images for a better understanding of the COVID-19 pandemic
por: Ismail, Alaa M., et al.
Publicado: (2020)

Multidimensional in silico strategy for identification of natural polyphenols-based SARS-CoV-2 main protease (M(pro)) inhibitors to unveil a hope against COVID-19
por: Adem, Şevki, et al.
Publicado: (2022)

Exploration of natural compounds against the human mpox virus DNA-dependent RNA polymerase in silico
por: Abduljalil, Jameel M., et al.
Publicado: (2023)

Clean Grinding Technique: A Facile Synthesis and In Silico Antiviral Activity of Hydrazones, Pyrazoles, and Pyrazines Bearing Thiazole Moiety against SARS-CoV-2 Main Protease (M(pro))
por: Abu-Melha, Sraa, et al.
Publicado: (2020)

Orbital Mucormycosis: Understanding the Deadly Fungus Sweeping the Globe
por: Farooq, Shaheen, et al.
Publicado: (2023)

In silico analysis of protein/peptide-based inhalers against SARS-CoV-2
por: Salman, Saad, et al.
Publicado: (2020)

Ciprofloxacin and moxifloxacin could interact with SARS-CoV-2 protease: preliminary in silico analysis
por: Marciniec, Krzysztof, et al.
Publicado: (2020)

In silico identification of conserved cis-acting RNA elements in the SARS-CoV-2 genome
por: Alhatlani, Bader Y
Publicado: (2020)

Mucormycosis: “The Black Fungus” trampling post-COVID-19 patients
por: Gupta, Ambika, et al.
Publicado: (2021)

COVID-19 and the alarming rise of “black fungus” (mucormycosis) infection
por: Khajotia, Rumi
Publicado: (2022)

Host-cell recognition of SARS-CoV-2 spike receptor binding domain from different variants
por: Elfiky, Abdo A, et al.
Publicado: (2022)

Inhibitory effect of garlic and omam extracts on Mucor circinelloides, a fungus causing mucormycosis: An in vitro study
por: Nimoshini, G, et al.
Publicado: (2023)

Synthesis and In Silico Study of Some New bis-[1,3,4]thiadiazolimines and bis-Thiazolimines as Potential Inhibitors for SARS-CoV-2 Main Protease
por: Gomha, Sobhi M., et al.
Publicado: (2022)

Overlapping host pathways between SARS-CoV-2 and its potential copathogens: An in silico analysis
por: Vavougios, George D.
Publicado: (2020)

In silico discovery of SARS-CoV-2 main protease inhibitors from the carboline and quinoline database
por: Muhtar, Eldar, et al.
Publicado: (2021)

In silico exploration of enzymes involved in sialic acid biosynthesis and their possible role in SARS-CoV-2 infection
por: Divya, V.C., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pfvi89b5embs6932mecmi5s9jt